Synthesis of a new spirocyclic lactam derivatives from 3-halogeno-3-trifluoroacetyl-1-methyl-2-pyrrolidinones
3-Bromo and 3-chloro-3-trifluoroacetyl-1-methyl-2-pyrrolidinones by the halogenation reaction of the corresponding 3-trifluoroacetyl derivatives. Characteristic hydrates after simple filtration on silica gel. The formation of new spirocyclic lactams.
Подобные документы
On the basis of experimental studies and mathematical modeling, the choice of optimal conditions for 2,3-dimethylbuta-1,3-diene and 2-hydroxyethyl methacrylate cyclization reaction with obtaining of 2-hydroxyethyl-1,3,4-trimethylcyclohex-3-carboxylates.
статья, добавлен 23.02.2016By Reaction with Alkyl Halides. Nucleophilic Addition. Oxidation of Ring Carbon Atoms Followed by Addition. Reduction of Exocyclic Double Bonds. Ring Cleavage Reactions. Coupling of Pyrazol-3-ones with Aryl Diazonium Salts. Oxidative Coupling, silylation.
учебное пособие, добавлен 05.03.2013The basic properties of alkoxides. Production technology of alkali metals alkoxides. Direct Synthesis in the Interaction of Metal and Alcohol. Interaction Metals Oxides and Hydroxides with Alcohols. Exchange reactions with alcohols, transesterification.
статья, добавлен 28.07.2017Models of 5,10-methylenetetrahydrofolate in organic synthesis and their reactions. Syntheses using mononucleophiles and binucleophiles. Molecular mechanism of carbon transfer reactions. Designs of models of coenzyme 5,10-methylenetetrahydrofolate.
статья, добавлен 05.03.2013Reactivity and Annulation of Another Ring to an Isoxazole Ring. Reactivity at the Ring Atoms. Reactivity of the Substituents. Syntheses of Condensed Heterocyclic Systems from Aminoisoxazoles. Ring Openings and Rearrangements. Synthesis of Aminoisoxazoles.
статья, добавлен 05.03.2013Investigations concerning the processes of plugging stone structure formation, using X-ray diffraction, electronic microscopy were implemented. Influence of active mineral additives of metakaolin on the properties of plugging mortar were established.
статья, добавлен 21.12.2016Study of kinetic parameters and the basic kinetic regularities of aldol condensation reaction of propionic acid with formaldehyde on B2O3-P2O5-WO3/SiO2 catalyst in the gas phase. Methods of obtaining polymer materials with valuable technical properties.
статья, добавлен 23.02.2016Influence of increasing the temperature of thermochemical activation of up to 750 °C and increasing the dosage of potassium hydroxide to 2.1 g/g of activated carbon synthesis of hydrolytic lignin on the formation of adsorption properties of the AC.
статья, добавлен 30.07.2017Changes of structural and power parameters of molecules of Laevomycetinum, conditioned by adsorption. Descriptors of biological activity of Laevomycetinum are energy of НВМО and length sanctify O hydrogen - H.O in the propanediol fragment of molecule.
автореферат, добавлен 02.04.2014History of the free element. Isotopes, properties: physical, chemical. Potassium cations in the body. Biochemical function, membrane polarization. Filtration, excretion, potassium in the diet and by supplement. Applications: biological, food, industrial.
реферат, добавлен 13.11.2009Study of influence of amino acids on the hydroxyapatite formation. Study of mineral obtained by transmission electron microscopy and powder X-ray diffraction. Analysis of the phase composition, crystal size and lattice microstrains of calcium phosphate.
статья, добавлен 23.12.2016Reviews on "Heterocyclic Compounds" on aspects such as synthesis, reactionmechanisms, structure complexity, properties, reactivity, stability, fundamental and theoretical studies, biology, biomedical, pharmacology, applications in material sciences.
материалы конференции, добавлен 05.03.2013It has been shown that well crystallized cobalt- and iron-containing spinel ferrites are formed at neutral pH value of aqueous medium. The contact of steel surface with alkaline medium results in formation of weakly crystallized iron oxyhydroxides.
статья, добавлен 04.04.2014A review on novel ring transformations of dinitropyridones and nitropyrimidinones. The synthesis of functionalized molecules, such as nitroanilines, nitropyridines by the ring transformation of dinitropyridones as the nitromalonaldehyde equivalent.
научная работа, добавлен 05.03.2013The method of synthesis of fluorinated heterocycles. The use of mono- and 1,3-dicarbonyl substrates and their nitrogen-containing analogues. Biological activity, physical and chemical properties of heterocyclic compounds with perfluoroalkyl groups.
научная работа, добавлен 05.03.2013Structure, a composition, a biological role, synthesis and catabolism of phospholipids. Conversion of Squalene to Cholesterol. Determination of interdependence of the deficiency of hydrolytic enzymes and lysosoms support sphingolipidosis development.
презентация, добавлен 05.10.2015Applications heterocyclic compounds; approaches to synthesis. Familiarization with effective conversion of organic compounds into valuable fluorinated products. The use of fluorinated triazoles for the protection of metals and alloys from corrosion.
научная работа, добавлен 05.03.2013The structural, theoretical and synthetic properties of enamines which act as important intermediates in many syntheses of organic compounds containing oxygen. Cycloaddition reactions, electrochemistry, hydrolysis and biochemistry of metalated enamines.
книга, добавлен 05.03.2013Study of the reaction of polyelectrolytes. Research of the structure and membrane properties of sodium carboxymethylcellulose and urea-formaldehyde oligomer. Development of technology for manufacturing biocompatible polymeric materials for medicine.
статья, добавлен 17.02.2019The use of cation exchanger as a catalyst for the esterification reaction of diisopropyl ether absolutes - a method for creating waste-free technology for the production of isopropyl alcohol. The physical-chemical properties of received esterificates.
статья, добавлен 20.09.2018A new amine-functionalized graphene oxide nanosheet was prepared via covalently grafting reaction. Results showed that adsorption capacity of GO was significantly improved by amine functionalization. The Langmuir isotherm and pseudosecond kinetic model.
статья, добавлен 15.01.2021General properties of organometallic complexes. Metal alkyls and hydrides. Nucleophilic and electrophilic addition. Physical methods in organometallic chemistry. Insertion and Elimination. Homogeneous catalysis. Applications to organic synthesis.
книга, добавлен 05.03.2013Investigation of the influence of electronic effects of substitution of maleic anhydride with hydrazine in acetic acid. Determination of CO stretching vibrations in the middle of the strip plane strain. Characteristics of magnetic shifts quinazolines.
статья, добавлен 17.02.2014Study of ternary intermetallic compounds RxMyXz (R = rareearth Element, M = d-metal, X = p-metal). Results of identification of the new R-Au-Al compound. The starting materials for the synthesis of R-Au-Ga. Function of the profile form of pseudo-Voigt.
статья, добавлен 23.02.2017Heterocycles with one, two, three and four heteroatoms. Fused heterocycles incorporating pyridine rings. Quinolines, isoquinolines, and their fused rings. Spiroheterocycles and a solvent-free one-pot reaction of a mixture of meldrum’s or barbituric acid.
учебное пособие, добавлен 05.03.2013