Symptom association probability and symptom sensitivity index: preferable but still suboptimal predictors of response to high dose omeprazole
A comparative study of the test results for omeprazole as an objective indicator of symptoms caused by reflux. Assessment of the severity and frequency of heartburn. Symptomatic response to high doses of omeprazole. Quantification of this relationship.
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The focus on symptom-based definition for gastroesophageal reflux disease in adults and children. The different reflux phenotypes, the utility of esophageal reflux testing, the mechanisms underlying symptoms, and the management strategies for phenotype.
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