Optimization of [(2-r-quinazolin-4-ylidene) hydrazono]carboxylic acids and esters – approach for creating a new class of compounds with the anticancer activity
Strategy of the search and working out of novel effective anticancer agents via optimization of [(2-R-quinazoline-4-ylydene) hydrazono] carboxylic acids and their esters. Approach for creating a new class of compounds with the anticancer activity.
Подобные документы
Treatment of metabolic disorders in children and adults of all ages. Treatment with drugs based on L-carnitine. The sequence of manufacturing operations, which allows creating a quality product. Describing of flowchart of the technological process.
статья, добавлен 29.01.2016The main risk factors for nosocomial pneumonia, optimization of their prevention. Prevalence of nosocomial pneumonia in surgical and therapeutic wards. Determination of nurses' knowledge regarding the problem of prevention of hospital pneumonia.
статья, добавлен 28.04.2020The influence of dentin on the effectiveness of three antibacterial agents (triclosan, glutaraldehyde, NaOCl) on Streptococcus mutans, Streptococcus sobrinus, and Lactobacillus acidophilus. The agar diffusion method with and without bovine dentin discs.
статья, добавлен 29.03.2013The hepatorenal syndrome as the primary lesion of the liver with subsequent involvement of kidney tissue. Screening of laboratory markers as order to detect hepatorenal syndromeis. Creating and testing of a client-server intelligent information system.
статья, добавлен 30.08.2016The search for methods of influence on reparative osteogenesis is an urgent issue today in modern dentistry. The goal of our study was to find effective osteoregenerative drugs for the elimination of jaw defects. The production of xenografts.
статья, добавлен 26.12.2023Optimization of medical treatment and physiological stabilization during assistance to the wounded. Specialized assistance during evacuation and initial surgical stabilization of cranial trauma. Intensive therapy at the stage of aeromedical evacuation.
статья, добавлен 19.03.2024The treatment of congenital hip dislocation in older children and adolescents as a problem of orthopedics, caused by a variability of anatomical changes and the degree of dislocation. Prospects for extra-articular operations on the pelvic and femur.
статья, добавлен 05.01.2021Study of topical problems regarding the correct diagnostic and therapeutic process in patients with diabetes mellitus with cardiovascular disease. Analysis of hypertension as a multifactorial trait, which is a big risk for severe internal injuries.
статья, добавлен 27.07.2016Indications for the walking bleach technique. Bleaching agents for the whitening of root-filled teeth. Influence of bleaching agents used for the bleach technique on tooth tissue. Examination of root fillings, existing restorations and tooth substance.
статья, добавлен 29.03.2013Search for effective materials for endoprosthesis. Reducing the risk of infectious lesions and the development of aseptic instability after filling bone defects with calcium phosphate cement. Characteristic properties of allotransplants and autografts.
статья, добавлен 26.02.2023- 86. Methodical approach to the study of intersystem interaction of human cardiovascular system and brain
Electroencephalography like one of the main tools that allow to investigate brain and heart function without resorting radical surgical methods. Characteristics of the role of the functional mobility in psycho-physiological functions of a person.
статья, добавлен 29.10.2020 Analysis of physical status classification at the American Society of Anesthesiologists. Development of an alternative classification system for risk assessment. Innovative principles of the assessment of medical complications, dental modifications.
статья, добавлен 10.12.2013The concept and clinical picture of an adenoid cystic carcinoma as a rare form of a malignant tumor with epithelial origin. Justification of the choice of the scheme of its optimal treatment, surgical approach and the degree of radical tissue removal.
статья, добавлен 17.04.2018Published guidelines and position papers, along with Embase and the Cochrane Database were reviewed and summarized with the intent to propose a practical approach and management for healthcare providers and to standardize and improve the quality of care.
статья, добавлен 22.03.2020Medical and social determinants of health-oriented behavioral youth and ways to change the situation. Reducing the share of the working-age population and the country's labor potential as a consequence of negative trends in the health of young people.
статья, добавлен 22.02.2021The methodology of creating the guidelines for the system of health technology assessment, the main stages of the informative components of the National guidelines in health technology assessment. The assessment of the organizational consequences.
статья, добавлен 29.01.2016Pharmacological activity of the main derivatives of 1,5-benzodiazepines. Interaction of 4-phenyl- and 4-methyl-2,3-dihydro-1H-1,5-benzodiazepinones-2 with epichlorohydrin under various conditions. The use of hard and soft basic reaction systems.
статья, добавлен 30.10.2016AmBisome (liposomal amphotericin B) how the first drug approved for a treatment of visceral leishmaniasis by the U.S. Food and Drug Administration.Safe and effective agents to treat such infections. Support approval for drugs to treat tropical diseases.
статья, добавлен 11.03.2014Prospects for study of sulfones. Develop of the preparative method of alkylation of 4-methyl-2-oxo-1,2-dihydroquinoline-6-sulfinic acid with allyl bromide. Characteristic of synthesis scheme of 6-allylsulfonyl-4-methyl-1,2-dihydroquinoline-2-one.
статья, добавлен 24.02.2016The formation of the level of male sex hormones in ontogeny. Importance of the hypothalamus and the gonads in the development of the male reproductive system. The formation of female sex hormones. The activity of the ovaries after birth, menopause.
презентация, добавлен 21.02.2017- 96. Acquisition and Analysis of Electrogastrogram for Human Stomach Disorders – A Statistical Approach
Electrogastrogram as a non-invasive, cheap and painless method is performed on patients to investigate the stomach disorders. The anatomy of the stomach, electrodes positioning. Statistical parameters for dyspepsia patients and normal individual.
статья, добавлен 29.03.2020 Analysis of electroencephalogram data during brain stimulation with verbal stimuli of different levels of complexity. Research, assessment of the electrical activity of the cerebral cortex during tasks with two different stimuli: perceptual and semantic.
статья, добавлен 13.04.2023Создание Quantitative Structure–Activity Relationship в современной химии лекарств, его место в системе оценки мутагенности. Перспективные методы и уравнения QSAR. Проблемы экспертизы баз данных, выделения дескрипторов и выработки алгоритма QSAR–анализа.
реферат, добавлен 05.04.2016Analysis of Zaytsev's personal qualities, as well as the facts of his becoming a person, a talented surgeon, a professional in his business. The review of the directions of his medical, scientific and pedagogical activity, contribution made to medicine.
статья, добавлен 25.12.2016Studies on the antistress protective actions of peptides of the glyproline family: Pro-Gly-Pro, Pro-Gly, and Gly-Pro. Typical changes in the behavioral activity of rats in the elevated cross maze. Providing evidence of a significant increase in anxiety.
статья, добавлен 10.03.2014