Defining the role of gene deletion TP 53 in the diagnosis and prognosis of chronic lymphoproliferative neoplasms using the method of fluorescence in situ hybridization
The results of molecular cytogenetic studies in 60 patients with chronic lymphoproliferative neoplasms. Clonal deletions of TP 53 gene were detected in 20% of patients with CLPN: eight of 20 patients with B-cell chronic lymphocytic leukemia (B-CLL).
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