Prospects for using exometabolites of mesenchymal stem cells as an antimicrobial agent
The article examines the influence of living mesenchymal stem cells (MSCs) and biologically active substances secreted by them (exometabolites, or secretions) on bacterial cells and their colonies, as well as on immunocompetent cells of the host's body.
Подобные документы
Mesenchymal stem cells are one of the most promising new treatments for human diseases. Morphometric study of microscopic parameters of the area in the fracture area in rats when using mesenchymal stem cells, the source of which was Warton's jelly.
статья, добавлен 20.03.2024Study of morphometric indicators of bone tissue of rats when using mesenchymal stem cells from Warton's gills against the background of a fracture. A review of the effect of mesenchymal stem cells on the treatment of fractures when administered locally.
статья, добавлен 17.06.2024Wide recognation in recent years of the consept of tumour stem cells, tumour initiating-cells, their role is in the processes of sarcomogenesis. Properties of tumor stem cells (renewal, high migration potential, high level of resistanse to chemotherapy).
статья, добавлен 30.10.2016Stem cells application, as one of the promising methods to treat pathologies of the musculoskeletal system. The effectiveness of local and systemic administration of cryopreserved autologous bone marrow multipotent mesenchymal stromal cells (MMSCs).
статья, добавлен 28.02.2016Study of migratory and differential potential of different types of stem cells, the relevance of this problem and approaches to its solution in biology and regenerative medicine. Ability to differentiate cells in the neural way after transplantation.
статья, добавлен 30.10.2016Analysis of the state of experimental researches that touch biological properties, prospects of application of barrel cages of placenta as them source. The personal interest of bioengineering of osteohondrous constructions is in mesenchymal barrel cages.
статья, добавлен 30.10.2016Аn analysis of the current literature of the scientific world community was carried out, in which studies describe stem cell therapy as a promising way to improve the results of the restoration of bone tissue that has a poor ability to regenerate.
статья, добавлен 04.12.2023Reports on the development of protocols of isolation of mesenchymal stem cells from umbilical cord blood and launch services of their long-term banking. Consideration of clinical trials to study the efficacy of such cells in the treatment of diseases.
статья, добавлен 28.02.2016Stem cell types in the breast. The role of estrogen and BRCA1 gene in hereditary breast cancer. Regulation of stem cells. Analysis of the achievements predecessors embryonic, fetal and adult stem cells in the treatment of hereditary breast cancer.
статья, добавлен 29.12.2012The role of immune cells in protecting the human body from pathogens and viruses. The influence of biologically active nutrients and bioactive substances in enhancing human innate and adaptive immunity for the prevention of COVID-19 in the population.
статья, добавлен 24.02.2024Stem cells application in neural system injuries. The determination of the level of tissue damage in hippocampus after in vitro model of ischemia and to investigate the effect of bone marrow MMSСs in non-contact co-culture with ischemic neural tissue.
статья, добавлен 28.02.2016Investigations on the use of stem cells for regeneration of damaged tissues, the use of cord blood as its source. Study of damage medial and extreme peripheral areas of the retina animals after application of injections. Assessment of the optic nerve.
статья, добавлен 27.08.2016Evaluation of the value and prospects of using cord blood stem cells in the treatment of cardiovascular diseases. Experimental and clinical studies of the effectiveness of treatment of ischemic and non-ischemic heart diseases using stem cells.
статья, добавлен 16.06.2024Research results demonstrated that immobilized cells of Lactobacillus acidophilus on the hydrogel of methylsilicic acid had enhanced protection not only against harsh conditions of the gastrointestinal tract (low pH and bile influence) but also against.
статья, добавлен 15.09.2024Improved myocardial contractility. Reducing end-diastolic volume. Significant improvements in functional capacity of patients with chronic heart failure and quality of life. Transplantation of stem cells of fetal origin in treatment as effective method.
статья, добавлен 24.02.2016The use of stem cell transplantation in the treatment of ischemic and degenerative diseases of the nervous system. Influence of transplantation gokhnari narallah progentor cells on endogenous neurogenesis, its evaluation in the ischemic animals.
статья, добавлен 28.02.2016The atomic force microscopy data and functional characteristics of oncogene cells. The increase resistance to the damages by oxidative substances. Factors of the chromosome instability. Structure and function of oncogene-transfected immortal cells.
статья, добавлен 27.03.2016The possibility of applying stem cell transplantation to treat ischemic and degenerative diseases of the nervous system. Influence of transplantation hippocampal neutral progenitor cells on endogenous neurogenesis in mice after ischemia-reperfusion.
статья, добавлен 24.02.2016Bradykinin receptor 2 as an attractive therapeutic agent for glioma patients. A high antiproliferative activity in the human glioblastoma cells U373. Effect of nonapeptide bradykinin antagonists on U373. BKM-570 as a potential anti-cancer agent.
статья, добавлен 27.03.2016The acquaintance with the peculiarities of the Shannon entropy. Consideration of the stages and fundamental characteristics of the formation of a unified informational complex DNA. An analysis of the advantages of fractal packing of DNA inside cells.
курсовая работа, добавлен 10.07.2016Creation of an antitumor drug based on biologically active substances of wormwood. Possibility of using the drug in the complex treatment of oncological diseases. Clinical determination of living cells by fluorescence spectroscopy.
статья, добавлен 01.09.2021Osteoarthritis is the most common degenerative joint disease that affects one or more joints. Comparison of the results of the treatment using Wharton's jelly stem cells and the classical combined method in people with osteoarthritis of the knee joint.
статья, добавлен 24.06.2024The role of glucose in the proliferative activity of tumor cells. Analysis of the microenvironment preceding the transition of tumor cells from an adhesive to a non-adhesive state. Effect of glucose on metabolic plasticity of Lewis lung carcinoma cells.
статья, добавлен 20.03.2024Opportunities for and barriers to progress in stem cell research for regenerative medicine. The ethical, moral and religious problems to use of embryos for stem cell research. Evidence supporting the potential of ESCs for use in regenerative medicine.
книга, добавлен 05.07.2013Chemotherapy as one of the major tool in the treatment of breast cancer. The main etiology of the development of drug resistance of cancer cells to chemotherapeutic agents. Analysis of the effect of anticancer drugs on the cells of breast carcinoma.
статья, добавлен 27.03.2016