Calix[4]arene alfa-hydroxymethylphosphonic acids as potential inhibitors of protein tyrosyne phosphatases
The combination of a macrocyclic platform and alfa-hydroxymethylphosphonate group for the inhibition activities of compounds. Computer-simulated docking studies using AutoDock 4.2 programme by the example of PTP1B. Stereoisomeric forms of the inhibitors.
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Critical reviews on "Heterocyclic Compounds" within topic-related volumes dealing with all aspects such as synthesis, reaction mechanisms, structure complexity, reactivity, stability, biology, pharmacological aspects, applications in material sciences.
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