Defining the role of gene deletion TP 53 in the diagnosis and prognosis of chronic lymphoproliferative neoplasms using the method of fluorescence in situ hybridization
The role of genomic disorders of chromosome 17 in the region 17p13.1, where gene of malignant transformation TP53 is localized in substrate cells of bone marrow. The results of cytogenetic studies in patients with chronic lymphoproliferative neoplasms.
Подобные документы
Hashimoto's thyroiditis is chronic autoimmune thyroiditis. The relationship between Hashimoto's thyroiditis and vitamin D deficiency. Some studies suggest that autoimmune thyroiditis results from a synergistic effect of genetics and environmental factors.
статья, добавлен 29.12.2023Description of the histological changes that accompany the development of fibrosis in the pancreas. Investigation of the features of expression of proapoptotic nuclease markers and proliferation at different stages of development of chronic pancreatitis.
статья, добавлен 29.01.2017Study the effect of EMAP II, IFN- 2b and its medicinal preparations on the amount of O6-methylguanine-DNA methyltransferase (MGMT) protein in human cells in vitro. The effect of medicinal preparations. Changes in the methyltransferase gene expression.
статья, добавлен 29.01.2017- 79. Natriuretic peptides-guided therapy in chronic heart failure: relevance to outcomes and survival
Discussion and research of specific features of the modern strategy of guided chronic heart failure therapy. Identification and characterization possible prospects for improved survival of patients through the timely correction of pharmacotherapy.
статья, добавлен 14.07.2016 Review of the literature that examines the effect of changes in the vaginal microbiome, chronic endometritis on the development of endometrial hyperplastic processes in women. The role of factors in the development of endometrial hyperplastic processes.
статья, добавлен 27.02.2023The need for detailed morphological studies of peripheral lung cancer that occurs on a background of chronic lung disease. The peripheral location of the scar and the presence of signs of chronic inflammation. Area of tumor complexes with "cancer pearls".
статья, добавлен 13.01.2017Investigation of the chronic heart failure and type 2 diabetes mellitus, which are closely inter-related conditions through different pathological mechanisms. Characteristic features of the platelets abnormalities according to glycemic control status.
статья, добавлен 24.02.2016The results of clinical use of mTOR inhibitors, in particular, everolimus, in immunosuppressive therapy regimens. Reasons why immunosuppressive therapy regimens including mTOR inhibitors are preferred in patients with high and moderate risk of graft loss.
статья, добавлен 28.02.2016Conducting a comprehensive analysis of trends in the incidence and prevalence of chronic cystitis among the male population. Determining the probability of change in the situation in the near future in the direction of increasing cases among men.
статья, добавлен 22.03.2022Study of results of treatment of patients using the device Targon DR. The clinical effect of the treatment through the impact of the devices on the shared recovery of bone after fracture, preservation of reduction, and achieve good functional results.
статья, добавлен 21.03.2016- 86. Acquisition and Analysis of Electrogastrogram for Human Stomach Disorders – A Statistical Approach
Electrogastrogram as a non-invasive, cheap and painless method is performed on patients to investigate the stomach disorders. The anatomy of the stomach, electrodes positioning. Statistical parameters for dyspepsia patients and normal individual.
статья, добавлен 29.03.2020 Symptoms of neurological disorders. Social support for patients. Therapies used in neurology. Prophylaxis of nervous system diseases. Care of patients with paralysis, paresis; who are comatose. Features of the nurses working in the neurology department.
презентация, добавлен 16.03.2016The atomic force microscopy data and functional characteristics of oncogene cells. The increase resistance to the damages by oxidative substances. Factors of the chromosome instability. Structure and function of oncogene-transfected immortal cells.
статья, добавлен 27.03.2016Leukotrienes play an role in inflammation and its sequelae: pain, swelling, bone resorption. their history, structure, synthesis, metabolism, biological effects, inhibitors, antagonists, and their role in pathogenesis of pulpal and periapical disease.
статья, добавлен 29.03.2013The study influence of the cardio-nephroprotective therapy on serum markers of cardiovascular risk in patients with chronic kidney disease. The possibility of practical use of FGF-23 and Klotho as an early diagnostic marker of cardiovascular risk.
статья, добавлен 19.04.2018Analysis of diagnostic diagnostic methods for early diagnosis of uterine carcinosarcoma used in medicine. Characteristics and features of diagnosis and timely selected treatment tactics. Image of a right ovarian mass with high metabolic activity.
статья, добавлен 09.08.2022Аn analysis of the current literature of the scientific world community was carried out, in which studies describe stem cell therapy as a promising way to improve the results of the restoration of bone tissue that has a poor ability to regenerate.
статья, добавлен 04.12.2023Research, analysis of the history of medicine, which forms new ideas about the formation of blood groups. Prerequisites for the emergence of the "vegetarian" second blood group A. The homeland of the gene of the third group B. The fourth blood group AB.
статья, добавлен 20.02.2023Changes in the system of erythropoiesis in the comorbid course of chronic obstructive pulmonary disease and urolithiasis of oxalate genesis. Influence of iron deficiency anemia of moderate severity, anemia of a chronic disease or a combination thereof.
статья, добавлен 01.12.2017A retrospective analysis of the results of the treatment of patients with resectable advanced oral squamous cell carcinoma. The analysis involved the patients who have undergone primary surgery, adjuvant radiotherapy, concomitant chemoradiation therapy.
статья, добавлен 24.02.2021The results of psychological characteristics of patients with attacks of a stenocardia in coronary heart disease, myocardial infarction, hypertensive crisis in patients with arterial hypertension, stroke and transient ischemic attacks were investigated.
статья, добавлен 22.01.2017The use of biochemical markers of connective tissue metabolism disorders in respiratory diseases in humans and animals. Diagnosis of chronic bronchitis and asthma in dogs and cats using cytokines (interleukin, interferon) and bronchoalveolar lavage.
статья, добавлен 25.04.2022The diagnostic criteria for primary intra-osseous salivary gland neoplasms. The mandibular adenoid cystic carcinoma with clinical and radiological features mimicking a periapical lesion. The difficulties of accurate diagnosis and the prediction.
статья, добавлен 05.03.2013Wide recognation in recent years of the consept of tumour stem cells, tumour initiating-cells, their role is in the processes of sarcomogenesis. Properties of tumor stem cells (renewal, high migration potential, high level of resistanse to chemotherapy).
статья, добавлен 30.10.2016Lifestyle interventions to increase longevity and improve metabolic balance are discussed. Exploring the role of metabolite analysis, which provides accurate data on nutrient deficiencies, metabolic imbalances, environmental toxins, microbiome status.
статья, добавлен 14.04.2022