Development and investigation of emulsion form for antiepileptic drug carbamazepine
Obtain a carbamazepine nanoemulsion for intravenous administration. The nanoemulsions were evaluated concerning droplet size, zeta potential and drug content. Preliminary studies of anticonvulsant activity for resulting formulation were carried out.
Подобные документы
Drugs based on the 1,2,4-triazole have a wide spectrum of biological activities. They are effective cardioprotectors, hepatoprotectors, anti-oxidants. Compounds with strong diuretic activity have been found among the newly synthesized compounds.
статья, добавлен 13.01.2017The using nickel powders as electrode materials in multilayered ceramic capacitors. Development of technology of Ni/NiO nanopowders obtaining with particle size of 20 nm and minimal impurities content. The analyses of powder microstructure the products.
статья, добавлен 30.07.2016Determination of biological activity of newly synthesized physiologically active substances. Study of antimicrobial activity, inhibits the development of gram-positive and gram-negative microorganisms. The features of systematic studies of 4-ticinonline.
статья, добавлен 28.01.2017Definition and characterization of the alginate-hydroxyapatite beads that potentially which can be used for drug release due to the adsorptive properties. Investigation and consideration of the main features of alginatecontrolled crystallization.
статья, добавлен 30.07.2016Conducting a study of the activities of the assay and analytical laboratory to determine the gold content in gold-containing products. Atomic absorption, tetrometric and assay-gravimetric analysis methods for determining the gold content in products.
статья, добавлен 31.08.2020Physicochemical characterisation of casein micelles suspended in milk ultrafiltrate and enriched with different cations: Fe, Cu, Ca. The order of association of cations with casein micelles. Changes in hydrophobicity, zeta potential of casein micelles.
статья, добавлен 20.11.2013Physical and chemical properties of the drugs. Reactions to chloride ions Cl- in a solution of AgNO3 in HNO3. Photocolorimetry with painted ferum hydroxamate. Reaction on heterocyclic atom of nitrogen. Using of methods of quantitative determination.
презентация, добавлен 24.11.2016Radical polymerization with a thiol-type chain transfer agent of poly-N-vinylpyrrolidone-based amphiphilic polymers, which can be used as drug carriers. Critical micelle concentration and its dependence on the molecular weight of the diblock copolymers.
статья, добавлен 18.04.2022Classification of terpenes. Diterpenes - organic compounds of terpenes group consisting of 4 isoprene units. Properties. Application. Drugs of the triterpene saponins. Gliderinin. Bioslastilin. Physical and chemical properties of triterpene saponins.
презентация, добавлен 15.01.2017Consideration of toxicity of the nanoparticles of the different elements. Investigation the effect of geometry (shape, size) of silver nanoparticles on their cytotoxicity. Shape, critical diameter, crystal lattice parameters of the nanoparticles.
статья, добавлен 25.02.2016- 11. Hydrodynamics modeling of gas separator inertial and filter elements for natural gas fine cleaning
The trends in the development of modern gas separation equipment have been considered. On the basis of computer modeling the optimal size of the device has been obtained. Reasonable choice of a computer and mathematical experiments has been shown.
статья, добавлен 21.12.2016 The combination of a macrocyclic platform and alfa-hydroxymethylphosphonate group for the inhibition activities of compounds. Computer-simulated docking studies using AutoDock 4.2 programme by the example of PTP1B. Stereoisomeric forms of the inhibitors.
статья, добавлен 29.01.2016Features of the laboratory experiment with exposure to cadmium salt solution and growth processes peroxidise activity in seedlings Pinus Sylvestris. Features of influence of cadmium ions on peroxidise activity and accumulation of 15-day-old cultures.
статья, добавлен 27.10.2016The objects of the cultural heritage discovered by archaeologists on the area of ancient Kyiv. The topographical examination the fragments of gold tissues (XI–XVI ad.). Content two kinds of materials: golden spiral threads and light colour flakes.
статья, добавлен 01.04.2014Friction units for automotive and special vehicles are designed to operate under friction conditions. The development of a unified understanding of the effect of the size and chemical nature of ceramic additives on the processes occurring in a friction.
статья, добавлен 22.05.2022Development of a method of mixing the hydroxides for the preparation of Lі[Ni0.5Co0.25Mn0.25]O2 from the respective products. Determination of average grain size, the measurement of impedance. Study of electrochemical properties using cyclic voltammetry.
статья, добавлен 21.12.2016The ultrasonic cavitation activity in aqueous solution of carbon dioxide was studied. The ICA-3M cavitometer was used for cavitation activity estimation. Erosion rate was estimated in a number of regimes. The spectra of cavitation noise were recorded.
статья, добавлен 19.02.2021Studies on interactions of nanomaterials with components of biosystems, development of new medicines based on magnetite, their application efficiency, chemical engineering of multilevel magnetosensitive nanocomposites with a hierarchical architecture.
статья, добавлен 02.04.2014Effect of polymerization copolymers on selenophenes and thiophenes. Analysis of electrosynthesis of selenofen-thiophene copolymers at a constant electrode potential. Stability of oxidation-reduction activity in electrolyte solution based on acetonitrile.
статья, добавлен 30.08.2016The development of selective oxidation of simply accessible dihydroxy-dypropoxycalix[4]arene to nitrocalixmonoquinone by mixture of 75 % nitric acid and glacial acetic acid. Synthone for design of optical sensors and redox-sensitive bio-active compounds.
статья, добавлен 11.02.2014Synthesis of folate-ferrocene conjugate (FFC) through a stage of synthesis ferrocene carboxylic acid. Confirmation of the structure of the conjugate by the methods of spectroscopy. Studies of the biological activity of FFC by the method of tissue culture.
статья, добавлен 21.12.2016Microporous structure of outgoing and thermally modified plant-extracted carbon material. Porous system characteristics by different methods on low temperature adsorption-desorption. Сharacteristic of most effective thermal modifications form nanopores.
статья, добавлен 24.02.2016Investigation of the influence intercalation ions of Ni2+ on the electrical properties of indium selenide crystals. The surface of InSe layered crystals. Investigation of magnetic properties of intercalated NiXInSe. The basic samples of InSe.
статья, добавлен 30.07.2016The study of the effect of bismuth nitrate (Bi (NO3) 3) deposited on tissue samples, coated tissue was evaluated by measuring the penetration of radiation. Various properties, such as mass per unit area, material thickness and surface morphology.
статья, добавлен 06.07.2020Alkylation of potassium 9-R1-10-R2-3-R-2-oxo-2Н-[1,2,4]triazino[2,3-с]quinazolin-6-thiolates by N-cycloalkyl-(cycloalkylaryl-)-2-chloracetamides. Analizes of indicators of the antiviral activity of compounds 3.2 and 3.14 against influenza type A H3N2.
статья, добавлен 29.01.2016