Modeling of molecular processes underlying parkinson’s disease in cells of methylotrophic yeast hansenula polymorpha
Abnormal oligomerization and aggregation of the protein alpha-synuclein, their connection with neurodegenerative diseases. The study of heat-resistant strains of methylotrophic yeast Hansenula polymorpha as a key in the pathogenesis Parkinson's disease.
Подобные документы
??????????? ???????? ???????? Hansenula polymorpha ? ???????????? ??????????? ???????. ?????????? ??????? ??????????? ???????. ????????????? ???? ????????, ?? ????????? ??????????? ????????, ???????????? ???? ???????????? ????????? ?????? ??????????.
???????????, добавлен 28.07.2014The ability of yeast strains to sbravati lactose in a medium containing whey powder and lactose in different concentrations. The decrease in the synthesis of ethanol when the concentration of substrate, its resistance in microaerophilic conditions.
??????, добавлен 29.01.2016????????? ????? ?????????????? ????????? ??????????????? ????????? ?????????????? b2 ? ?????? ?????????????? ?????????? ??????????? ???????? - ????????????? ???????? H. polymorpha. ????????? ????? ?????????????? ?????? ?? ?????? ??????????????.
???????????, добавлен 25.02.2015???????? ??? ?????? ????????? ?? ?????? ????????, ?? ???? ? ?????? ???????????? ??????????. ?????????????? ????? Cdc13 ? ?????? TERT (???????? ????????? ????????????? ?????????), ?????? ??????? Cdc13 ? ??????????? ?????????? ?? ???????? H. polymorpha.
??????, добавлен 17.08.2020??????????? ??????? ????????? ????????????? ?????? ?? ????????? ???????????????? ??????? MIG1. ???????? ????? ???????????? ???????? ?? ??????????? ????????? ????????? ??? ????????? ?????????????? ?????? ??? ?????????? ???? ????????????? ????????????????.
???????????, добавлен 14.09.2015????????????? ?? ???????????? ????, ?? ????????? ?? ????????? ??????? ? ????????????? ??????. ??????????? ????????????? ????????????? ?????????? ?????. ?????????? ???????-???? ???????????? ????? ??????. ???????? ?????????? ???????????? ??????????.
??????, добавлен 28.08.2016???????? ?????? ????? ?? ?????? ???????? ?? ?????????? ???????? ?? ????????????. ????? ????????????? ???????? ? ????? ?????????? ????? ???????. ???????? L-??????-??????????? ??????????????? ??????????? ? ????????????? ????????????????? ??????????.
???????????, добавлен 29.09.2015??????????? ??????????????? ????? Dreissena polymorpha. ?????????? ??????????? ?? ?????????? ?????? ?????? ?????????? ???????? ????????. ????????? ???????????? ?????? ?????????????? ?????? ? ?????. ?????? ?????????? ?? ???????-?????? ?????? 2014-2015 ??.
??????, добавлен 23.12.2021????????????? ?????????????? ?????? ???????? ? ????????? ?????????? ?????, ????????? ? ????????? ????? ??????????? ??????? (????????????? ??? ???????? ??? XYL1, ???? XYL2 ?? XYL3). ???????????-?????????? ?? ??????????? ?????? ?????????????? ??????.
???????????, добавлен 25.08.2015Characterization and study of bacterial diseases on agricultural crops and weeds under different cropping systems. The definition of biological properties, identification of pathogens, traditional and modern molecular-genetic methods of research.
??????, добавлен 29.01.2016Since the advent of recombinant DNA technology three decades ago, thousands of eukaryotic genes have been isolated. The differential expression of these genes is critical for both normal cellular processes and abnormal processes associated with disease.
?????, добавлен 05.07.2013Mechanisms for the identification of yeast cultures by polymerase chain reaction. Morphological and biochemical properties of the culture. The specificity of fermentation a carbohydrates and hydrogen sulfide formation from different grape varieties.
??????, добавлен 13.09.2016??????? ?????? ????????? (Ath1p) ? ??????????? ????????? ?? ?????????????????? H. polymorpha. ????????????? ?????? H. polymorpha ? ?????????? ??????????????????? ???????????? ??????? ?? ??????? ???????????? ???? PDC1, ???? ????? ?????????????????????.
???????????, добавлен 19.07.2015?????? ????????? ????????????? ? ???????? ???????????? ? ?????????????? ??????????? ?? ?????? ????????????? ? ????????? ????????. ??????????? ???????? ?????????. ????????? ?????? ??????????? ? ????? ???????? ????????-??????????? Dreissena polymorpha.
??????, добавлен 25.09.2016The use of disease and pest resistant species in landscape design contributes to the effectiveness of green plantings. For this purpose, the pests Berberis L. and control measures in the dry subtropical climate of the Absheron Peninsula were studied.
??????, добавлен 14.02.2025Study of polyhydroxyalkanoates, which are aliphatic polyesters. The process of synthesis and accumulation of aliphatic polyesters in bacterial cells. Obtaining a low molecular weight copolymer with a high content of monomers in bacterial cells.
??????, добавлен 13.04.2022Identification of local strains of Bacillus thuringiensis. Determination of genotypes and phenotypes using methods of molecular biology and biochemical tests. Variation in strains associated with different types of toxins, as well as genetic variations.
??????, добавлен 22.02.2023Study the role of the small molecular inhibitor PFKFB3 in lung cancer. Search for effective ways to restore cell viability. Decoding the effect of KAN0438757 on proliferation, migration, and programmed cell death in non-small cell lung carcinoma cells.
??????, добавлен 12.05.2024Amyloid fibrils, which include PAP248-286 and PAP85-120 fragments of prostatic acid phosphatase. Studying the features of oligomers of SEVI-forming peptides by constructing their molecular models that have proven their effectiveness in the study of SEVI.
??????, добавлен 03.03.2023Study of the process of membrane fusion. Analysis of proteins derived from the zitoplazmaticakih membranes. Opening of homologous proteins from yeast to neurons checks the General idea. Characteristics of biochemical synthesis of biological membranes.
??????? ???????, добавлен 05.07.2013Using the laws of physics and chemistry in the process of building cells. Technological gene information as instructions on the sequence of cell formation. Conditions for the functioning of information processes in living cells. Eternity of life cycle.
??????, добавлен 15.04.2024To study the influence of the rat progenitor neurogenic cells supernatant on the peripheral blood mononuclear cells (PBMC) of patients with brain gliomas and to compare it with influence of the preparation with established immunomodulatory properties.
??????, добавлен 18.12.2023The importance of microvesicles and exosomes in cellular and molecular biology, their role in intercellular communication, in the processes of cell detoxification and regeneration. The use of exosomes in the therapy of tumors and autoimmune diseases.
??????, добавлен 16.06.2024The study of variability of the morphology of pollen grains of the genus Pinus. Differences in the total amount of abnormal pollen under the influence of pests and pathogens of different nature. The possibility of diagnosing of biotic influence on plants.
??????, добавлен 04.12.2023DNA: Structure, function. Basic techniques in gene analysis. Polymerase chain reaction. Protein production and purification. Genome sequencing projects. Post-genome analysis. Engineering animal cells. Engineering animals. Transfection of animal cells.
??????? ???????, добавлен 25.11.2013