Synthesis, physico-chemical properties and prognosis of the pharmacological activity of 4-phenyl-5-(1,2,3-benzotriazolyl-1)-3-mercapto-1,2,4-triazole(4H) derivatives
The study of the synthesis and physicochemical properties of derivatives of 4-phenyl-5-(1,2,3-benzotriazolyl 1)-3-merkapto-1,2,4-triazole(4H). Due to computer prognosis data the substances synthesized are prospective anticonvulsants and antiasthmatics.
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Drugs based on the 1,2,4-triazole have a wide spectrum of biological activities. They are effective cardioprotectors, hepatoprotectors, anti-oxidants. Compounds with strong diuretic activity have been found among the newly synthesized compounds.
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