Natural and hybrid ("chimeric") stable regulatory glyproline peptides
The concept of relative instability of regulatory peptides in the issues and fluids of organism. The historical facts of glyproline investigation. Antiulcer effects of intraoperational, intragastic administrations at etanol-induced damages in rats.
Подобные документы
Structural resemblance glyproline peptide family. Studing a simplest proline-containing linear peptides PG, GP, PGP. The suppression of reactions of blood coagulation and platelet aggregation and protection of gastric mucosa against ulcerogenic factors.
статья, добавлен 10.03.2014Intranasal administration of Semax, peptide Pro-Gly-Pro, and a mixture of peptides ProGly+Gly-Pro to rats enhanced anticoagulant and fibrinolytic potential of the plasma) and decreased antiplasmin concentration. Semax decreased the weight of thrombi.
статья, добавлен 10.03.2014The various physiological actions on the brain of melanocortin. The cloning of neural receptors. The effects of neuropeptides on the nervous system. Relationships of peptides derived from adrenocorticotropic hormone with cloned receptors in vitro.
статья, добавлен 10.03.2014Investigation of target organs vulnerable to obesity. Function of compensation of a metabolism at excess of fat in an organism. Morphological characteristics of glomeruli, tubules of the kidneys. Introduction of melatonin against glomerular degeneration.
статья, добавлен 20.09.2020Studies of the characteristics of serum albumin in rats with different predicted levels of resistance to emotional stress in control conditions and in conditions of experimental emotional stress. The effects of peptides the resistance of animals.
статья, добавлен 10.03.2014The pharmacodynamic effects of niftolide and other androgen receptor antagonists from the group of substituted carboxanilides that had been synthesized locally were studied. Development of new methods for treatment of androgen-dependent prostate cancer.
статья, добавлен 26.12.2023The studies of the effects of the ACTH(4–10) analog Semax (MEHFPGP) on the behavior of white rats with lesions to the brain dopaminergic system induced by the neurotoxin MPTP. The neurotrophic action of the peptide. Induced lesions of the brain.
статья, добавлен 10.03.2014The increase secretory activity of mast cells in the mesentery and subcutaneous fat of rats. Intraperitoneal injection of Semax and prolyl-glycyl-proline. Secretory activity of mast cells in unstressed animals. The stabilizing effect of peptides.
статья, добавлен 10.03.2014The effect of a high-calorie diet in obesity on the morphological structure of the kidneys. Correction of their condition with using melatonin. Evaluation of pathological changes in the tubules, glomeruli of the kidneys in comparison with obese animals.
статья, добавлен 20.09.2020The work on prophylaxis and therapy of steroid-induced Impaired glucose tolerance with metformin preparation having a number of therapeutic effects on human organism besides main hypoglycemic activity in patients with skin diseases was carried out.
статья, добавлен 29.09.2016To study the effects of regular endurance exercises on total oxidant status (TOS) and total antioxidant status (TAS) parameters in liver tissues of rats that are experimentally made to acquire hyperthyroidism (excessive production of thyroid hormone).
статья, добавлен 16.12.2020Memantine has an individual therapeutic effect on Alzheimer’s disease. The testing the influence of memantine on memory processes in young rats. Whether memantine really affects memory processes, or its action is directed to other accompanying processes.
статья, добавлен 25.06.2022Peroral administration of Pro-Gly peptide before provocation of thrombin generation and thrombus formation prevented death of animals from thrombosis. Analysis of experiment on rats with venous thrombosis induced by stasis and administration of thrombin.
статья, добавлен 10.03.2014The effect of a diazepinone on purine and lipid metabolism in liver of rats with Parkinson’s disease caused by rotenone by studying the composition of bile. Diazepinone improves the metabolism of purines and lipids in liver of rats with ROT-simulated PD.
статья, добавлен 05.06.2022The Motors of Stasis and Change: The Regulation of Genetic Stability. The Meaning of human Gene Function: What Does a Gene Do. The concept of a Genetic Program: How to Make an Organism. Limits of Genetic Analysis What Keeps Development on Track.
учебное пособие, добавлен 05.07.2013The problem of assessing the participation of autonomic support of mental activity in terms of heart rate. Investigation of the level of activation of regulatory mechanisms of heart rhythm during the increase of the speed of verbal, image processing.
статья, добавлен 18.12.2020Cutaneous melanoma as an aggressive oncological disease with early growth of metastasis. Acquaintance with promising targets for targeted therapy. Consideration of the features of blocking the process of metastasis. Analysis of antitumor agents.
статья, добавлен 17.04.2018The analysis of the existing polarizational methods of investigation of the body's tissue. Determination of effectiveness when using laser polarizational methods of the research of ischemic damages taking acute myocardial ischemia as an example.
статья, добавлен 25.12.2016Investigation of biochemical and cytomorphological changes in the oral mucosa of rats when deprived of plant food. Study of the effect of long-term deficiency of plant polyphenols in the diet of experimental animals on the state of the oral mucosa.
статья, добавлен 17.02.2021- 20. Natriuretic peptides-guided therapy in chronic heart failure: relevance to outcomes and survival
Discussion and research of specific features of the modern strategy of guided chronic heart failure therapy. Identification and characterization possible prospects for improved survival of patients through the timely correction of pharmacotherapy.
статья, добавлен 14.07.2016 Anti-inflammatory properties of SnCl4 with benzaldehyde and 4-bromobenzaldehyde salicyloyl hydrazones the were studied in the rats using models on carrageenan and formalin-induced inflammation of paw. The anti-inflammatory activity in both models.
статья, добавлен 21.10.2021Osteogenic potential of calcium hydroxide and other materials in soft tissue. Calcium hydroxide as an bone inducer in rats. Ultrastructural study of initial calcification in the rat: subcutaneous tissues elicited by a root canal filling material.
статья, добавлен 05.03.2013The atomic force microscopy data and functional characteristics of oncogene cells. The increase resistance to the damages by oxidative substances. Factors of the chromosome instability. Structure and function of oncogene-transfected immortal cells.
статья, добавлен 27.03.2016Analysis of the effects of 2 chemical retraction agents on gingival blood flow and systemic blood pressure in subjects with healthy gingival were investigated. investigation and assessment of the impact on blood flow gingival retraction gingival.
статья, добавлен 05.03.2013- 25. The consequences of electromagnetic field exposure on the spermatogenesis process in rat's testes
Determine the effects of the electromagnetic field of high voltage and low frequency on the genitals of male rats. Study the number of degenerative forms of spermatozoa forming as a result of mitotic and meiotic disorders at the stage of late spermatids.
статья, добавлен 31.01.2024