Thermodynamics of 3-hydroxy-7-bromo-5-(2'-chloro) phenyl-1,2-dihydro-3h-1,4-benzodiazepine-2-ones esters complexation with the central benzodiazepine receptors
The complexation of 3-alkylcarbonyloxy-7-dihydro-3Н-1,4-benzodiazepine with the central benzodiazepine receptors at six temperatures. The ester carbonyl groups in compounds 1 and 2 are also supposed to form different hydrogen bonds with the receptor.
Подобные документы
The study of the synthesis and physicochemical properties of derivatives of 4-phenyl-5-(1,2,3-benzotriazolyl 1)-3-merkapto-1,2,4-triazole(4H). Due to computer prognosis data the substances synthesized are prospective anticonvulsants and antiasthmatics.
статья, добавлен 05.03.2014Study crystallographic sequence of the phase transition in zirconium dioxide at heated. The transformation of monoclinic phase in tetragonal modification. The appearance of new anion vacancies, which form at evaporation of the oxygen from the lattice.
статья, добавлен 30.07.2016Changes of structural and power parameters of molecules of Laevomycetinum, conditioned by adsorption. Descriptors of biological activity of Laevomycetinum are energy of НВМО and length sanctify O hydrogen - H.O in the propanediol fragment of molecule.
автореферат, добавлен 02.04.2014Study of ternary intermetallic compounds RxMyXz (R = rareearth Element, M = d-metal, X = p-metal). Results of identification of the new R-Au-Al compound. The starting materials for the synthesis of R-Au-Ga. Function of the profile form of pseudo-Voigt.
статья, добавлен 23.02.2017- 30. Calcium
There are notable characteristics, occurrence, applications (compounds, H and K lines), history, compounds, isotopes, nutrition (dietary calcium supplements, prevention of fractures due to osteoporosis, possible cancer prevention, overdose) about calcium.
реферат, добавлен 13.11.2009 Applications heterocyclic compounds; approaches to synthesis. Familiarization with effective conversion of organic compounds into valuable fluorinated products. The use of fluorinated triazoles for the protection of metals and alloys from corrosion.
научная работа, добавлен 05.03.2013Drugs based on the 1,2,4-triazole have a wide spectrum of biological activities. They are effective cardioprotectors, hepatoprotectors, anti-oxidants. Compounds with strong diuretic activity have been found among the newly synthesized compounds.
статья, добавлен 13.01.2017The applications of leuco-dyes, of spiro compounds and tetrazolium salts. The transformation of the molecules in thermal and photo-imaging systems. Leuco compounds which are not formed by reduction of the parent dye. The chemistry of the phthalides.
книга, добавлен 05.03.2013Consideration of the results of x-ray diffraction of the considered chemical compounds. Structural properties of the films of magnesium oxide. Substantiation of optimum parameters of temperature of synthesis of organic and many inorganic compounds.
статья, добавлен 30.07.2016- 35. Reactions of 1-(4-hydroxyphenyl)-3-(4-nitrophenyl)-5-ethyl-1,2,4-triazole with electrophilic agents
To synthesize new biologically active compounds, the reactions of electrophilic substitution of 1-(4-hydroxyphenyl)-3-(4-nitrophenyl)-5-ethyl-1, 2, 4-triazole (I) have been studied. The structure of the new compounds was confirmed by 1H NMR spectra.
статья, добавлен 27.07.2016 Phase analysis and the crystal structure of the compounds has been investigated by means of X-Ray analysis. Magnetic properties of two synthesised compounds were investigated revealing paramagnetic behaviour in whole investigated temperature range.
статья, добавлен 20.07.2022A new universal method of estimating the chemical shifts values of the methylene groups. Change the values of 1H and 13C each methylene group in the result of the conversion by replacing the long fragments –(CH2)K– and –(CH2)I– of the Vice alculated.
статья, добавлен 23.02.2016Study of synthesis of silica-based organic-inorganic hybrid materials with grafted 2-aminoethylpyridine functional groups. By elemental analysis to determine the composition of substances. Analysis of surface-structural characteristics of SiAEP.
статья, добавлен 02.04.2014A procedure of a sol-gel method for synthesis of new polysiloxane xerogels with propionic and butyric acid-type groups. Structure of some carboxylic groups. Scrutiny specific surface areas of polysiloxane xerogels and average pore diameter of samples.
статья, добавлен 18.03.2014A comparison of the transition and nontransition metal ion complexes has been done. The absorption spectra provide that the reagent is more and selective for manganese than other metals. The electronic absorption measurements at different pH-values.
статья, добавлен 23.01.2021Synthesis of sorption-active material carrying groups 5% chlorosulfonic acid by radiation-induced graft polymerization of styrene monomer on the surface of non-woven polypropylene fabric with subsequent sulfonation of the grafted polystyrene chains.
статья, добавлен 02.04.2014- 42. The experimental study of the effect of raleukin on development of dithizone diabetes in rabbits
Diabetes mellitus in the structure of endocrine diseases. The study of the effect of antioxidant properties of a biological product is a recombinant receptor antagonist Il-1 relacin and hypoglycemic action for major reaction non-enzymatic glycosylation.
статья, добавлен 29.01.2016 The chemical structure of the polymer latexes. The influence of surfactants on the drip solution. The mechanism of anionic with a negative charge in the screed, acting as air entrainment. Hydrogen bonding, water absorption and compressive strength.
статья, добавлен 22.02.2015Brief biographical information about the life of F. Haber - a German chemist and Nobel laureate. Investigation the reaction of nitrogen with hydrogen, which produces ammonia. The essence of Le Chatelier's Principle. The main function of the catalyst.
реферат, добавлен 04.02.2015Reviews on "Heterocyclic Compounds" on aspects such as synthesis, reactionmechanisms, structure complexity, properties, reactivity, stability, fundamental and theoretical studies, biology, biomedical, pharmacology, applications in material sciences.
материалы конференции, добавлен 05.03.2013Polymers, inorganic and organic, amorphous and crystalline substances consisting of "Monomeric units" connected in a long macromolecule chemical bonds. Molecular modeling of melting process of solid polymers in the transition and plastic deformation.
статья, добавлен 23.02.2016Examined of the physical-chemical properties and thermal decomposition, as well as infrared spectrum of glass. Acquaintance with the results of the derivatographic analysis. Study of the coincidence of crystallization temperatures of glass decomposition.
статья, добавлен 26.02.2021A review on novel ring transformations of dinitropyridones and nitropyrimidinones. The synthesis of functionalized molecules, such as nitroanilines, nitropyridines by the ring transformation of dinitropyridones as the nitromalonaldehyde equivalent.
научная работа, добавлен 05.03.2013Synthesation, physicochemical properties of nanopowders LaPO4-LuPO4-H2O and LaPO4-YPO4-H2O. Investigation of thermal behavior orthophosphate nanosized solid solutions. Discussion results of the experiment, solubility and melting temperatures of systems.
статья, добавлен 13.02.2015Plastic additives as a wide range of chemicals used by resin manufacturers, compounds and manufacturers to improve the properties, processing and characteristics of polymers. Features of their chemical composition and conditions of effective use.
статья, добавлен 10.03.2019