Molecular mechanisms of resistance of endometrial hyperplasia to progestagen therapy
The problem of resistance of atypical endometrial hyperplasia to traditionally accepted, pathogenetically justified therapy with various types of progestins remains. The aim of the study was to review the literature sources to clarify the reasons.
Подобные документы
Optimizing lipid-lowering therapy and achieving it in three ways: increasing the dosage of statins. The pathogenesis of immune inflammatory reactions and endothelial dysfunction ischemic heart disease in combination with systemic inflammatory diseases.
статья, добавлен 14.07.2016Natural products can be used as novel therapeutic interventions with improved pharmacological properties targeting tumor cells. Consideration of phytomedicines for adjuvant therapy, ability to diminish adverse effects of chemotherapy in cancer patients.
статья, добавлен 03.09.2024- 78. Allosteric site of serine proteinases: localization, functional role and manifestations in vitro
The study of molecular mechanisms of regulation of biologically active molecules. Role of serine proteinases in the regulation of physiological and pathogenic processes. The localization, functional role and manifestations of allosteric region.
статья, добавлен 03.09.2024 Device for the experimental study of the interaction of polarized light with samples of tissues. Discussion of practical reasons for making the system suitable for use in the dermatology clinic. Selecting the wavelength for different light sources.
статья, добавлен 28.09.2016The article analyzes data from the literature on the effects of cyclophosphamide, immunofan, salt extract of Hirudo verbana, tobacco smoke, formaldehyde, staphylococcal toxoid, light stress, ablation therapy on the structural components of the thymus.
статья, добавлен 28.12.2023The female reproductive system. Ovaries, yellow body of the uterus or fallopian tubes. Anatomy and histology of the uterus. Endometrial, vaginal and mammary glands. The development of female sex hormones, phase of reproductive and menstrual cycles.
презентация, добавлен 07.05.2015Gastroesophageal reflux is a common condition. The mechanisms of the disease: abnormal structure and function of the esophageal-gastric connection, violation of the clearance of the esophagus. Аcid suppression therapy test proton pump inhibitors.
статья, добавлен 02.03.2020The aim - of the scientific work was a review of the medical literature regarding the clinical and pharmacological rationale for the use of hyperproduction of pro-inflammatory cytokines by GCS in case of SARS-CoV-2 infection in clinical practice.
статья, добавлен 20.07.2024Genital herpes - one of the most socially important problem in clinical practice of dermatovenereologist, obstetrician-gynecologists. Antivirals of systemic effect and local action for herpetic infection therapy on pharmaceutical market of Ukraine.
статья, добавлен 29.11.2016Overexpression in many human cancers. Molecular docking of ZSTK474 derivatives as PI3Kbeta inhibitory agents. Review absorption, distribution, metabolism and excretion and possible pharmacological activity сhemical. Additional binding energy human.
статья, добавлен 30.10.2016Blood pressure lowering for prevention of cardiovascular disease and death: a systematic review. The evidence for use of beta-blockers as first line therapy for hypertension. Calcium channel blockers in hypertension. Medical treatment of the disease.
статья, добавлен 27.02.2021Small animal models of osteoarthritis are suitable for preclinical investigations of OA pathogenesis: its genetic and molecular mechanisms; large animal allow to investigate biomechanical changes of the joint and to provide intraarticular interventions.
статья, добавлен 30.07.2016The state of medical care for patients with epilepsy in Ukraine. The gender and economic aspects of diagnosis and therapy of the disease. The social side of this medical problem. Statistic data about the incidence of epilepsy in the developing countries.
статья, добавлен 22.01.2017Thirty immature sheep incisor teeth were tested for their fracture resistance after various treatment modalities using calcium hydroxide or a mineral trioxide aggregate material as a root filling. Comparison of calcium hydroxide or MTA in sheep teeth.
статья, добавлен 30.03.2013The peculiarities of the formation of the activity-operational component of the professional identity of future specialists in physical therapy, ergotherapy and to diagnose. The activity-operational component is manifested is implemented in stages.
статья, добавлен 19.03.2023Investigation of the chronic heart failure and type 2 diabetes mellitus, which are closely inter-related conditions through different pathological mechanisms. Characteristic features of the platelets abnormalities according to glycemic control status.
статья, добавлен 24.02.2016Investigation of the dynamics of the fibrinolytic activity of blood serum in surgical treatment of patients with benign prostatic hyperplasia. The procedure of transurethral resection. Features fibrinolysis status during intra- and postoperative periods.
статья, добавлен 30.01.2016Schizophrenia is an urgent problem in modern medicine. A study of the concentration of cytokines with pro-inflammatory and anti-inflammatory activity in individuals with different types of paranoid schizophrenia (continuously progressive and episodic).
статья, добавлен 12.07.2021The article discusses the author’s experience with monopolar and bipolar transurethral resection of the prostate for benign prostatic hyperplasia (BPH) performed in a total of 49 patients, approximately the same number of patients in each group.
статья, добавлен 20.06.2021The study of the emergence and spread of bacterial strains that cause infectious diseases and are resistant to antibiotics. Development of modern alternative approaches to antimicrobial therapy through targeting bacterial virulence and adhesion.
статья, добавлен 18.03.2016Issues and consequences of traumatic injuries. Ultrasound examination as a non-traumatic method of medical examination and a significant method of treatment of traumatic injuries. Mechanisms of action of ultrasound, advantages and limitations of its use.
статья, добавлен 16.06.2024Review of the influence of oral hygiene on the formation of microbiota in adolescents with chronic catarrhal gingivitis on the background of diabetes. Analysis of the rate of salivation, the viscosity of oral fluid, and the state of oral hygiene.
статья, добавлен 16.06.2024The modern international classification of postoperative ventral hernias, endoprostheses, postoperative complications, causes of unsatisfactory results. Long-term administration of drugs - the method of effective use of local tissue infiltration.
статья, добавлен 10.02.2021The possibility of predicting the results of laparoscopic fundoplication in patients with refractory gastroesophageal reflux disease using pH-impedance measurements of the esophagus, carried out before the operation, is being studied. Сlinical outcome.
статья, добавлен 22.02.2020Types of pathological changes in the oral mucosa in children with studied pathology. Dependence between the duration of time of the underlying disease used by the basic therapy, and the pathology of the oral mucosa in children with rheumatic diseases.
статья, добавлен 19.04.2018