Synthesis and diuretic activity of 2-(5-(phenoxymethyl)-4-r1-1,2,4-triazole-3-ylthio)acetic acids and their salts
Drugs based on the 1,2,4-triazole have a wide spectrum of biological activities. They are effective cardioprotectors, hepatoprotectors, anti-oxidants. Compounds with strong diuretic activity have been found among the newly synthesized compounds.
Подобные документы
- 26. Synthesis and crystal structure of an Ag(I) complex of composition (C9H7N(C3H5))2[AgBr2]Br(H2O)2
Coordination behavior of Ag (I) with cations of N-allyl quinolinium. Synthesis of N-allyl quinolinium bromide. Determination of the structure of the x-ray crystal. Bromine ions of the second crystallographic type. Study silver nitrate compounds.
??????, добавлен 23.02.2017 Some aspects of sugar-derived heterocycles and their precursors which are utilized as the inhibitors against glycogen phosphorylases and are responsible for the release of mono-glucose from poly-glucose. The quantitative structure-activity relationship.
??????? ??????, добавлен 05.03.2013- 28. The molecular structure and chromatographic parameters of calix[4]?r?nehydroxymethylphosphonic acids
A basic chromatographic characteristics of biologically significant calix[4]?renehydroxymethylphosphonic acids. A study sodium salts in a reversed-phase high-performance liquid chromatography. The structure of calix[4]?renehydroxymethylphosphonic acids.
??????, добавлен 05.03.2014 Isomeric aminobenzoic acid – an important chemical product of organic synthesis used in the production of synthetic dyes, medicinal and aromatic substances, wines, pesticides. Investigation the reaction of the oxidization of 2- and 3-aminotoluenes.
??????, добавлен 22.03.2016Reviews on "Heterocyclic Compounds" on aspects such as synthesis, reactionmechanisms, structure complexity, properties, reactivity, stability, fundamental and theoretical studies, biology, biomedical, pharmacology, applications in material sciences.
????????? ???????????, добавлен 05.03.2013Properties, combustion, electron energy levels. Elemental molecular forms. Covalent, organic compounds. Hydrides, protons, acids, isotopes. Discovery and use. Role in quantum theory. Natural occurrence, production: laboratory, industrial, thermochemical.
???????, добавлен 13.11.2009Carbon as the element essential to all of life, and hence the basis for a vast field of study. Electronegativity value of fluorine. Plastic polystyrene - important product of the hydrocarbon family. Chemical properties of carboxylic acids and esters.
??????, добавлен 15.09.2014A review on novel ring transformations of dinitropyridones and nitropyrimidinones. The synthesis of functionalized molecules, such as nitroanilines, nitropyridines by the ring transformation of dinitropyridones as the nitromalonaldehyde equivalent.
??????? ??????, добавлен 05.03.2013Prepared of n-aryl-2-[(4-amino-4H-1,2,4-triazol-3yl)thio] acetamides by interaction of amino-1,2,4-triazolyl-3thiol with n-aril-2-chloroacetamides and formation of n-aryl-2-[6,8-dimethyl[1,2,4]triazolo[4,3-b]pyradazin-3-yl)thio]acetamide derivatives.
??????, добавлен 18.02.2014The structural, theoretical and synthetic properties of enamines which act as important intermediates in many syntheses of organic compounds containing oxygen. Cycloaddition reactions, electrochemistry, hydrolysis and biochemistry of metalated enamines.
?????, добавлен 05.03.2013History of the nucleophilic substitution of hydrogen in aromatic compounds, obtaining picric acid. Survey of SNH Substitution. Heterocyclizations Based on SNH Reactions. Intramolecular One-Step SNH Cyclizations; cascade Sequences Based on SNH Reactions.
??????? ??????, добавлен 05.03.2013Study of ternary intermetallic compounds RxMyXz (R = rareearth Element, M = d-metal, X = p-metal). Results of identification of the new R-Au-Al compound. The starting materials for the synthesis of R-Au-Ga. Function of the profile form of pseudo-Voigt.
??????, добавлен 23.02.2017Study of swelling kinetics as compared to solvents of various nature (water in various pH, ethanol, toluene) was carried out. IR comparative spectra were obtained for different composites. High anti-bacterial action of the synthesized nanocomposites.
??????, добавлен 30.07.2016The ultrasonic cavitation activity in aqueous solution of carbon dioxide was studied. The ICA-3M cavitometer was used for cavitation activity estimation. Erosion rate was estimated in a number of regimes. The spectra of cavitation noise were recorded.
??????, добавлен 19.02.2021MPWB1K/6-31+G(d) and MPWB1K/tzvp theoretical models were found to provide reasonable accuracy of the prediction of ionization potentials for mono- and polycyclic azacompounds. The root mean square errors of the methods are 0.19 and 0.20, respectively.
??????, добавлен 30.10.2016Critical reviews on "Heterocyclic Compounds" within topic-related volumes dealing with all aspects such as synthesis, reaction mechanisms, structure complexity, reactivity, stability, biology, pharmacological aspects, applications in material sciences.
??????? ???????, добавлен 05.03.2013Characteristics: chemical properties, compounds, spectroscopy, isotopes. History, commercial production. Applications, biological role: maintaining body fluid volume in animals, maintaining electric potential in animal tissues. Dietary uses, precautions.
???????, добавлен 13.11.2009Phase analysis and the crystal structure of the compounds has been investigated by means of X-Ray analysis. Magnetic properties of two synthesised compounds were investigated revealing paramagnetic behaviour in whole investigated temperature range.
??????, добавлен 20.07.2022Rubidium as a chemical element and a soft, silvery-white metallic element of the alkali metal group. Characteristics, history, occurrence rubidium. Isotopes, uses and applications. Compounds, rubidium chloride. Precautions and biological effects.
???????, добавлен 13.11.2009Study of the synthesis of complexes of diacetylhydrazine with hydrazine hydrate. Carrying out the reaction of the ligand with cobalt in the presence of salts of metal chloride and furfural. Condensation of diacetylhydrazine with hydrazine monohydrate.
??????, добавлен 15.01.2021Advances in heterocyclic chemistry. Molecular cascade and the formation of heterocyclic compounds and their impact on cost and waste reduction in the use of natural resources for production, the impact on the environment, energy and resource conservation.
??????? ??????, добавлен 05.03.2013Magnesium as a chemical element and a silvery-white, light-weight metal. Notable characteristics, applications. As the metal. Incendiary use, in magnesium compounds. History, sources, ores, sea water, electrolysis. Biological role, isotopes, precautions.
???????, добавлен 13.11.2009Synthesis ferroelectric compounds Sr(B1/3Nb2/3)O3 by solid state reaction technique. Consideration of the correlation between the dielectric response and transport behavior. Emprovement dielectric material properties. Motion energy storage devices.
??????, добавлен 30.07.2016Synthesis of a methacrylic azomonomers based on para-aminoacetanilide to obtain functionalized polymers for orientation of liquid crystals. The kinetics of polymerization of synthesized azomonomers. Constants of thermo-induced radical polymerization.
??????, добавлен 21.12.2016To study antimicrobial properties of the synthesized surfactants, the method of consequent dilution was used. The experiments were carried out in the test tubes contained a surfactant at different concentrations and 1 ml of the physiological solution.
??????, добавлен 03.03.2021
