Corrective effects of benzodiazepine derivative - diazepinone on purine and lipid metabolism in the liver of rats with Parkinson’s disease
The effect of a diazepinone on purine and lipid metabolism in liver of rats with Parkinson’s disease caused by rotenone by studying the composition of bile. Diazepinone improves the metabolism of purines and lipids in liver of rats with ROT-simulated PD.
Подобные документы
The cellular and tissue therapy like the technology, which is widely used in treatment of various diseases. Modern industrial development - the reason for the accumulation in the human body of a foreign toxic substances that can affect the liver.
статья, добавлен 27.02.2021Study changes in TDS and protein oxidative modification measures in the brain of rats with experimental diabetes mellitus when using cerebroprotectors. Activity of glutathione reductase (GR) and glutathione peroxidase (GP) in the DM rat brain tissue.
статья, добавлен 13.08.2016Role and significance of duodenogastric bile reflux in patients with gastroesophageal reflux disease. Biochemical studies of gastric contents. Development of duodenogastric reflux in gastroesophageal reflux disease. Clinical dynamics of the disease.
статья, добавлен 03.03.2020Studies of the characteristics of serum albumin in rats with different predicted levels of resistance to emotional stress in control conditions and in conditions of experimental emotional stress. The effects of peptides the resistance of animals.
статья, добавлен 10.03.2014- 55. Transcranial near-infrared therapy for cognitive performance and neurological status enhancement
The therapeutic potential of tNIR and its efficacy in stimulating cellular functions to improve outcomes in neurodegenerative diseases such as dementia, Parkinson's disease, Alzheimer's disease as well as traumatic brain injury, stroke recovery.
статья, добавлен 20.03.2024 Pathogenesis, risk factors for hemorrhagic stroke as a complication of essential hypertension. Diagnostic value of ultrasound examination of cervical arteries and heart, of changes in lipid metabolism and its relationship with the coagulation hemostasis.
статья, добавлен 21.07.2024The anthropomorphological examination of patients with Wilson’s disease. Studying the appropriate composition of this population and peculiarities of its structure. The association between this presence of pathology and Mediterranean phenotypic variant.
статья, добавлен 22.01.2017The impact of intra-arterial chemotherapy on the resectability of colorectal metastases in the liver and the results of the successful clinical case. Impact of the hepatic artery infusion on the resectability of hepatic metastases of colorectal cancer.
статья, добавлен 15.09.2024Pharmacokinetics of drug fate. The mechanism altering drugs absorption, distribution, metabolism. Identify drugs interactions, the mechanisms of older interactions, and examine the safety of new drugs from classes that are known to cause interactions.
статья, добавлен 10.12.2013Investigation of biochemical and cytomorphological changes in the oral mucosa of rats when deprived of plant food. Study of the effect of long-term deficiency of plant polyphenols in the diet of experimental animals on the state of the oral mucosa.
статья, добавлен 17.02.2021Comparative study of fertility, spermatogenesis and indicators of prenatal development of offspring male rats when co-administered anti-TB drugs. Introduction preparations containing isoniazid, pyrazinamide, rifampicin and ethambutol or streptomycin.
статья, добавлен 20.03.2016Analysis features of sweet woodruff (asperula odorata L.) of Rubiaceae Juss. family is not officinal plant, which is used in folk medicine as a sedative, diuretic and choleretic agent. Study of histological structure of liver of the experimental animals.
статья, добавлен 27.08.2016The first laboratory of systems biology in Ukraine. Study the response of primary hepatocytes to interferon. Development of a stoichiometric model of folate-related metabolism in human placenta. The system’s behavior at different human pathologies.
статья, добавлен 27.03.2016The concept and description of early left ventricular anomalies, the problems of their diagnosis using standard echocardiography in patients with hypertension and impaired glucose metabolism. Study of changes in their function by echocardiography.
статья, добавлен 13.01.2017Influence of the goutweed in the kidney and liver histological structure in mice with alloxan diabetes. Opposition to the development of necrosis and infiltration of protein renal tubules of mice after the administration of the infusion "Arfazetin".
статья, добавлен 24.02.2016The activity of the redox metabolism - the factor for trigger the cascade process in cells, that lead to a violation of the biochemical regulation of homeostasis by active oxygen ions. A link between oncoprocess and oxidative modification of proteins.
статья, добавлен 27.07.2021Features of morphostructural changes in the uterus of rats with prevailing hemodynamics disorder of the organ in NNLA-injection. Microcirculatory changes as a manifestation of vascular decompensation, accompanied by disturbances of blood rheology, etc.
статья, добавлен 13.01.2017Significant association between the high levels of atherogenic lipids in the middle of pregnancy and an excessive increase in percentage of body fat mass in late terms. Disruption of adaptive metabolic changes in conditions of increased energy demand.
статья, добавлен 23.05.2023The ability of drugs to epigenetically affect gene expression is considered one of the likely mechanisms of unwanted side reactions. Whole-genome DNA methylation (MspI/HpaII) and its fragmentation in blood lymphocytes of rats against the background.
статья, добавлен 27.12.2023Conversion chemotherapy, its application. To evaluate the outcomes of patients with B/U liver metastases from CRC treated with conversion chemotherapy with the modified fluorouracil, leucovorin, and oxaliplatin (mFLOX) regimen followed by metastasectomy.
статья, добавлен 18.02.2021Overexpression in many human cancers. Molecular docking of ZSTK474 derivatives as PI3Kbeta inhibitory agents. Review absorption, distribution, metabolism and excretion and possible pharmacological activity сhemical. Additional binding energy human.
статья, добавлен 30.10.2016Peroral administration of Pro-Gly peptide before provocation of thrombin generation and thrombus formation prevented death of animals from thrombosis. Analysis of experiment on rats with venous thrombosis induced by stasis and administration of thrombin.
статья, добавлен 10.03.2014In the study effect ofportal hypertension on the condition of the hemomicrocirculatory tract of the skin male white nonlinear rats was studied. Hypertension was simulated by applying a ligature to the portal vein according to the conventional method.
статья, добавлен 06.06.2022The use of biochemical markers of connective tissue metabolism disorders in respiratory diseases in humans and animals. Diagnosis of chronic bronchitis and asthma in dogs and cats using cytokines (interleukin, interferon) and bronchoalveolar lavage.
статья, добавлен 25.04.2022Dynamics of Bcl-2- dependent anti-apoptotic activity in the hippocampal fields of rats with diabetes mellitus, global ischemia-reperfusion of the brain. Main role in pathogenesis of ischemic-reperfusion brain injuries and diabetic encephalopathy.
статья, добавлен 27.01.2021