Effect of anticancer drugs on breast cancer cells sensitive and resistant to doxorubicin: expression of mRNAs of TGF-b and its receptors
Chemotherapy as one of the major tool in the treatment of breast cancer. The main etiology of the development of drug resistance of cancer cells to chemotherapeutic agents. Analysis of the effect of anticancer drugs on the cells of breast carcinoma.
Подобные документы
Diagnostic and clinical parameters of the symptoms of the cancer disease of the small intestine. Complications that can be caused, as a result of a cancerous tumor. Comorbidities that occur suddenly and in need of treatment by surgical intervention.
презентация, добавлен 26.02.2014Differentiation between "driver" and "passenger" mutation as an important task for the functionalization of cancer genomics in the treatment of patients. Differences between mutations that lead to the growth of a mutational nucleus from benign mutations.
статья, добавлен 19.02.2021Multi-disciplinary and endovascular approach to the treatment of kidney cancer. Clinical description of the operation for a male patient with intraparenchymatous kidney cancer and a postoperative course complicated by a rare vascular pathology.
статья, добавлен 25.11.2020Non-adjuvant polychemotherapy - technology that indicates the presence of chemo-resistant tumor cells. Molecular-biological markers of tumors - certain chromosomal and gene mutations that involved in the development, progression of malignant diseases.
статья, добавлен 11.08.2021Research results demonstrated that immobilized cells of Lactobacillus acidophilus on the hydrogel of methylsilicic acid had enhanced protection not only against harsh conditions of the gastrointestinal tract (low pH and bile influence) but also against.
статья, добавлен 15.09.2024Treatment of peptic ulcer, anticholinergic drugs that inhibit the action of the vagus nerve on acid-secreting cells, contraindications to use. Recommendations of helicobacter pylori eradication. Prevention , symptoms and treatment of chronic pancreatitis.
презентация, добавлен 08.02.2015Conversion chemotherapy, its application. To evaluate the outcomes of patients with B/U liver metastases from CRC treated with conversion chemotherapy with the modified fluorouracil, leucovorin, and oxaliplatin (mFLOX) regimen followed by metastasectomy.
статья, добавлен 18.02.2021Assessment of the results of clinical genealogical and molecular-genetic observation of patients with ovarian cancer. The rationale for its role as an important step for the creation of genetic risk groups for the development of neoplasia in the family.
статья, добавлен 01.12.2017Investigating the value of the systemic inflammation index as a potential biomarker for predicting cancer recurrence. Analysis of the correlation between the level of the index and the risk of recurrence of cancer in patients with oncological disease.
статья, добавлен 08.06.2024Generalization of the results of the implemented studies and definition of a strategy for further research in the direction of preventing the development of occupational cancer in Ukraine. Conditions for reforming the national health and safety system.
статья, добавлен 28.12.2017Improved myocardial contractility. Reducing end-diastolic volume. Significant improvements in functional capacity of patients with chronic heart failure and quality of life. Transplantation of stem cells of fetal origin in treatment as effective method.
статья, добавлен 24.02.2016The antitumor immunity in patients with cancer of the oral cavity, oropharynx during treatment (chemoradio therapy), which additionally included immunotherapy with a/f-defensin. Dose-dependent decrease in the relative number of lymphocytes in the blood.
статья, добавлен 12.06.2022Atherosclerosis: Signal Transduction by Oxygen and Nitrogen Radicals. Apoptotic Pathways in Cancer Progression and Treatment. Molecular and Cellular Aspects of Insulin Resistance: Implications for Diabetes. Neurotrophic Signaling in Mood Disorders.
книга, добавлен 05.07.2013The need for detailed morphological studies of peripheral lung cancer that occurs on a background of chronic lung disease. The peripheral location of the scar and the presence of signs of chronic inflammation. Area of tumor complexes with "cancer pearls".
статья, добавлен 13.01.2017The frequency of infectious complications after operations of patients with colorectal cancer (CRC) as an indicator of the quality and safety of surgical care. Dependence between complications and long-term results of radical surgical treatment of CRC.
статья, добавлен 17.04.2018Study of morphometric indicators of bone tissue of rats when using mesenchymal stem cells from Warton's gills against the background of a fracture. A review of the effect of mesenchymal stem cells on the treatment of fractures when administered locally.
статья, добавлен 17.06.2024Development and implementation of non-invasive methods for diagnosing prostate cancer. Selection of optimal combinations of biomarkers of the state of the prostate. Evaluation of the value of spermine content in determining the stage of the tumor process.
статья, добавлен 22.03.2022The results of treatment of the esophageal cancer in relation to dose received. Results of the associated radiation therapy of the esophageal cancer. The further improvement of the combined use of combined radiation therapy with radiochemomodificators.
статья, добавлен 22.03.2018Genetic, cellular, tissue and circulating markers in Tumors. Diseased regulatory pathways. Growth Factor-Signaling Pathways in Cancer. Antitumor immunity as therapy for human cancer. Invasion and Metastasis. Emerging molecular therapies for the disease.
книга, добавлен 05.07.2013The distribution of glycoproteins in the cells of the major salivary glands in early postnatal period after intrauterine antigen action. Changes in cells of the salivary glands, which is the basis for the development of inflammatory processes in them.
статья, добавлен 27.06.2016Study the effect of EMAP II, IFN- 2b and its medicinal preparations on the amount of O6-methylguanine-DNA methyltransferase (MGMT) protein in human cells in vitro. The effect of medicinal preparations. Changes in the methyltransferase gene expression.
статья, добавлен 29.01.2017The article examines the influence of living mesenchymal stem cells (MSCs) and biologically active substances secreted by them (exometabolites, or secretions) on bacterial cells and their colonies, as well as on immunocompetent cells of the host's body.
статья, добавлен 15.09.2024Strategy of the search and working out of novel effective anticancer agents via optimization of [(2-R-quinazoline-4-ylydene) hydrazono] carboxylic acids and their esters. Approach for creating a new class of compounds with the anticancer activity.
статья, добавлен 30.10.2016The atomic force microscopy data and functional characteristics of oncogene cells. The increase resistance to the damages by oxidative substances. Factors of the chromosome instability. Structure and function of oncogene-transfected immortal cells.
статья, добавлен 27.03.2016To study the effect of echinacea purple extract on the number of cells a single layer of epithelium in one gastric hole. Determining the number of cells in one's own gland mucosa. Glandular pit epithelial cell index of the rats' stomach fundus of rats.
статья, добавлен 06.02.2017