A comparative analysis of the crystal structure of R,S-racemate and R-enantiomer of 7-bromo-3-(2-methoxy)ethoxy-5-phenyl-l,2-dihydro-3H-1,4-benzodlazepine-2-one exhibiting a high analgesic activity
The crystal structure of racemate R,S-7-bromo-3-ethoxy-5-phenyl-3H-1,4-benzodiazepine- has been compared to the structure of R-enantiomer. It has been determined that crystals of R-enantiomer and R,S-racemate are formed by the similar H-bonded chains.
Подобные документы
Study the interaction of an order of amino-anthraquinones with benzoylisothiocyanate. The process of obtaining the formation of new N-benzoyl-N '- (9,10-dioxo-9,10-dihydroanthacen-1- yl) -thioureas. Quantumchemical analysis of the passing reaction.
статья, добавлен 23.02.2016The efficiency of using softened water in the removal of dissolved oxygen and iron ions has been determined. The dependence of the efficiency in the processes of the deoxygenation and iron removal of water on the filtering speed through the redox filter.
статья, добавлен 26.02.2021Investigation of optical absorption spectra of YAG: Cr, Mg, and GGG: Cr, Mg films during high-temperature annealing in oxidation and reduction atmospheres. Factors to increase in absorption in the visible region, the charge exchange of chromium ions.
статья, добавлен 29.09.2016Research modifications in the process of protective coating forming while heating. Examination of interaction between silicium organic compounds based on the rich polymethylphenylsiloxane. Opportunities of their utilization for high-temperature.
статья, добавлен 24.02.2016New facile method for the controllable synthesis of high quality single-phase nanowires with from nanowires templates. Detailed characterization of the superconducting and transport properties of nanowires. Synthesis of porous nanowires and nanotubes.
статья, добавлен 30.07.2016Anodic deposition of own and extrinsic hydroxides on aluminium from electrolyte was studied by voltastatic method at low and high voltages. The mechanism of precipitation using the conception of fast neutralization coagulation, the models of nucleation.
статья, добавлен 27.07.2016Shannon’s entropy and Weighted entropy. Weighted entropy and it’s applications. Ranking chemicals in quantitative High Throughput Screening. The studies of weighted entropy. Weighted entropy in Bayesian problem, as a measure of an investment risk.
магистерская работа, добавлен 30.08.2016Tetrahydroxycalix[4]arene, tetraalkoxycalix[4]arenes and tetraalkylcalix[4]resorcinarenes are capable to reversible adsorption on the surface of the hydrophobic support lichrosorb RP 18. Conditions reversed high-performance liquid chromatography.
статья, добавлен 28.08.2016Study crystallographic sequence of the phase transition in zirconium dioxide at heated. The transformation of monoclinic phase in tetragonal modification. The appearance of new anion vacancies, which form at evaporation of the oxygen from the lattice.
статья, добавлен 30.07.2016The modification action of polyvinylpyrolidone on morphological peculiarities of magnesium hydrosilicate powder has been investigated. The most effective modification method is observed during joint precipitation of the system liquid components and PVP.
статья, добавлен 30.08.2016The method of synthesis of fluorinated heterocycles. The use of mono- and 1,3-dicarbonyl substrates and their nitrogen-containing analogues. Biological activity, physical and chemical properties of heterocyclic compounds with perfluoroalkyl groups.
научная работа, добавлен 05.03.2013The article discusses solutions to the problem of recycling wood waste and its use as a raw material for the production of new high-quality materials for industries. The purpose is to obtain composite materials containing wood waste and epoxy resin.
статья, добавлен 08.01.2021Convenient method of synthesis of optically active oxamoylaminoacids. Compounds have significant hepatoprotective, antiinflammatory and immunodepressant activities with low toxicity. Influence of investigated sudstances on rarametrs of specific immunity.
статья, добавлен 15.02.2014Search of bioactive substances containing in the molecule a heterocycle and a deputy with high antioxidant properties such as succinic acid. Antibacterial and cytotoxic action of Di-Na-salt. Methods of di-Na-salt of 2-(pyridine-4-iltio)succinic.
статья, добавлен 29.01.2017This work analyzes ternary phase diagrams of magnesium with two rare-earth metals of different subgroups, conducted in IMET RAS in connection with the development of high-temperature magnesium alloys. A lot number of phase diagrams were discovered.
статья, добавлен 23.02.2017The problem of identification of paints according to the commodity nomenclature of foreign economic activity. Chemical composition are received, structures, and other organoleptic, physical and chemical parameters of production of paints and varnishes.
статья, добавлен 10.03.2018The efficient synthetic protocol for aminomethylation proceeding was developed which led to obtaining a series of novel 3-(phenylamino)-methyl derivatives of 5,7-dimethyl-6-phenylazo-3Н-thiazolopyridin-2-one. The conditions for aminomethylation reaction.
статья, добавлен 30.08.2016Changes of structural and power parameters of molecules of Laevomycetinum, conditioned by adsorption. Descriptors of biological activity of Laevomycetinum are energy of НВМО and length sanctify O hydrogen - H.O in the propanediol fragment of molecule.
автореферат, добавлен 02.04.2014Physical parameter models. Thermodynamic parameter models. Brief review of the relationship between the solution model and phase equilibria. The modified quasi chemical (MQC) model. Basic quasi chemical theory. The modified binary quasi-chemical theory.
статья, добавлен 10.04.2017Treating the properties of oxidized activated carbon KAU by different temperatures in inert atmosphere were studied by means of DTA, Boehm titration, XPS and AFM methods and their catalytic activity in hydrogen sulphide oxidation was established.
статья, добавлен 04.04.2014Obtain a carbamazepine nanoemulsion for intravenous administration. The nanoemulsions were evaluated concerning droplet size, zeta potential and drug content. Preliminary studies of anticonvulsant activity for resulting formulation were carried out.
статья, добавлен 30.07.2016Features silver nanoparticles were produced using tannic acid solution as reducing and capping agent. Results of UV-Vis and XRD ensured the existence of silver nanoparticles in the final samples. Nanoparticles with different morphologies were detected.
статья, добавлен 30.07.2016The study of the processes of reparative activity diacamph part of the medications suppositories for the treatment of degenerative and inflammatory diseases of the rectum, determination of their crystallographic and thermogravimetric characteristics.
статья, добавлен 29.10.2016To study the activity of functional groups of polyurethanes, the characteristics of the stabilization process, the formation of silver nanoparticles. The use of antimicrobial polymeric materials. The interaction of hydrogen bonds between groups of biuret.
статья, добавлен 30.07.2016Physicochemical properties of 1-alkyl-5-methyl-6-(2-methyl-1,3-thiazol-4-yl)-3-phenylthieno[2,3-d]pyrimidine-2,4(1H,3H)-diones 3 and 4. The method for preparation of 5-methyl-6-(2-methyl-1,3-thiazol-4-yl)-3-phenylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione.
статья, добавлен 29.10.2016