Synthesis of some novel thiazolo[4,5-b]pyridines and their tuberculostatic activity evaluation
The efficient synthetic protocol for aminomethylation proceeding was developed which led to obtaining a series of novel 3-(phenylamino)-methyl derivatives of 5,7-dimethyl-6-phenylazo-3Н-thiazolopyridin-2-one. The conditions for aminomethylation reaction.
Подобные документы
The method of synthesis of fluorinated heterocycles. The use of mono- and 1,3-dicarbonyl substrates and their nitrogen-containing analogues. Biological activity, physical and chemical properties of heterocyclic compounds with perfluoroalkyl groups.
научная работа, добавлен 05.03.2013Tetrahydroxycalix[4]arene, tetraalkoxycalix[4]arenes and tetraalkylcalix[4]resorcinarenes are capable to reversible adsorption on the surface of the hydrophobic support lichrosorb RP 18. Conditions reversed high-performance liquid chromatography.
статья, добавлен 28.08.2016Synthesis and reactions of heterocyclic compounds in chemistry. Three- and four-membered heterocycles: heterocycles with one heteroatom (oxiranes, thiiranes, aziridines). Five-membered heterocycles: heterocycles with one, two, three and four heteroatom.
статья, добавлен 05.03.2013Determination of biological activity of newly synthesized physiologically active substances. Study of antimicrobial activity, inhibits the development of gram-positive and gram-negative microorganisms. The features of systematic studies of 4-ticinonline.
статья, добавлен 28.01.2017Brief biographical information about the life of F. Haber - a German chemist and Nobel laureate. Investigation the reaction of nitrogen with hydrogen, which produces ammonia. The essence of Le Chatelier's Principle. The main function of the catalyst.
реферат, добавлен 04.02.2015Electrochemical lithiation reactions of electrodes made of R5M3 alloys were studied in an organic electrolyte containing LiPF6 salt, using the conventional charge-discharge technique, and the reaction products were analyzed by X-ray powder diffraction.
статья, добавлен 23.02.2017- 57. Kinetics of liquid-phase hydrogenation of n-valeraldehyde to n-amyl alcohol over a Ru/Al2O3 catalyst
Schematic diagram of the experimental setup for hydrogenation. Effect of catalyst loading on initial rates of reaction. The use of gas chromatography for the analysis of the reaction. Langmuir–Hinshelwood-type models for single, dualsite mechanisms.
статья, добавлен 20.10.2014 The one-step procedure of simultaneous preparation of polyacrylonitrile-based carbon support and Fe-Pd bimetallic nanoparticles. The effect of synthesis conditions on the metal-carbon nanocomposite structural characteristics. The crystallite size.
статья, добавлен 27.08.2020Study of the process of intramolecular cyclization products of epichlorohydrin aminolysis of secondary amines. Analysis of the energy characteristics obtained in vacuum and in acetonitrile solution with water as an "active" solvation partner of reaction.
статья, добавлен 30.10.2016Hydrogen evolution reaction (HER) is the cathodic hydrogen evolution reaction in electrolytic cell, but the hydrogen evolution catalytic properties of electrode materials best remains is the precious metal catalyst, has become the research hot spot.
статья, добавлен 10.10.2024The ultrasonic cavitation activity in aqueous solution of carbon dioxide was studied. The ICA-3M cavitometer was used for cavitation activity estimation. Erosion rate was estimated in a number of regimes. The spectra of cavitation noise were recorded.
статья, добавлен 19.02.2021- 62. Synthesis and crystal structure of an Ag(I) complex of composition (C9H7N(C3H5))2[AgBr2]Br(H2O)2
Coordination behavior of Ag (I) with cations of N-allyl quinolinium. Synthesis of N-allyl quinolinium bromide. Determination of the structure of the x-ray crystal. Bromine ions of the second crystallographic type. Study silver nitrate compounds.
статья, добавлен 23.02.2017 Synthesis semizwitterionic viologens for the crystal engineering of functional materials. Application of the control positions of molecules in crystals using hydrogen bonds. The triple helices had obtained by tunig the spacer between donor and acceptor.
статья, добавлен 17.02.2014Mechanistic aspects of the Diels-Alder reaction. The effect of micelles on it. The effects of Lewis acids on the endo-exo selectivity in water compared to the effects in organic solvents. Enantioselective cid catalysis of an organic reaction in water.
книга, добавлен 05.03.2013Crystals of the [Cu(C4H7N3S)Cl] (1)-complex were synthesized by solvothermal reaction of 2-amino-5-ethyl-1,3,4-thiadiazole (C4H7N3S) with CuCl in hydrochloric acid solution, and studied by X-ray diffraction. 3D hydrogen-bonded framework in complex.
статья, добавлен 23.02.2017The specificity of the hydrothermal method for the synthesis of calcium carbonate. Determination of the nanostructure in the present inorganic chemical compound of salt carbonic acid and calcium. The diffraction characteristics of the calcium salt.
статья, добавлен 30.07.2016Determine the optimal parameters of synthesis and base properties of nano-tubular crystals Mg-Ni chrysotiles. temperature ranges and pressure for the synthesis of nano-tubular crystals all synthesed chrysotile at the time of isothermal exposure.
статья, добавлен 30.07.2016Monomers conversion dependence on reaction mixture composition. Consideration of the dependence cooligomer of and its characteristics, average molecular weight. Study of liquid products of pyrolysis of hydrocarbons: styrene and dicyclopentadiene.
статья, добавлен 23.02.2016The basic properties of alkoxides. Production technology of alkali metals alkoxides. Direct Synthesis in the Interaction of Metal and Alcohol. Interaction Metals Oxides and Hydroxides with Alcohols. Exchange reactions with alcohols, transesterification.
статья, добавлен 28.07.2017By Reaction with Alkyl Halides. Nucleophilic Addition. Oxidation of Ring Carbon Atoms Followed by Addition. Reduction of Exocyclic Double Bonds. Ring Cleavage Reactions. Coupling of Pyrazol-3-ones with Aryl Diazonium Salts. Oxidative Coupling, silylation.
учебное пособие, добавлен 05.03.2013Models of 5,10-methylenetetrahydrofolate in organic synthesis and their reactions. Syntheses using mononucleophiles and binucleophiles. Molecular mechanism of carbon transfer reactions. Designs of models of coenzyme 5,10-methylenetetrahydrofolate.
статья, добавлен 05.03.2013Reactivity and Annulation of Another Ring to an Isoxazole Ring. Reactivity at the Ring Atoms. Reactivity of the Substituents. Syntheses of Condensed Heterocyclic Systems from Aminoisoxazoles. Ring Openings and Rearrangements. Synthesis of Aminoisoxazoles.
статья, добавлен 05.03.2013Purines fused with five-membered heterocycles: pyrrolo-, oxazolo-, thiazolo-, imidazo-, pyrazolo-, triazolo- and tetrazolo-purines. Purines annulated with five-membered rings. Compounds with a greater selective efficacy without the unwanted side-effects.
статья, добавлен 05.03.2013Quantitative evaluation of the antimicrobial ability of silver nanoparticles in comparison with silver ions, evaluation of the antimicrobial effectiveness of silver nanoparticles when introduced into water-soluble paints, cotton fabrics, fibrous sorbents.
статья, добавлен 13.04.2022The cycle of sanitary and chemical investigations of various artificial leathers and the polymer composition. The possibility of conducting direct stabilization of artificial leathers. The hygienic evaluation of polymers and polymer-containing materials.
статья, добавлен 29.01.2016