Prospects for the JNK kinase inhibitors use in the treatment of dyslipipemic conditions
JNK inhibitors in biomedical experiments. The study of the molecular mechanisms of development of damage and adaptation of cell systems at the pathological conditions of different genesis. The apoptosis and the imbalance of oxidative metabolism.
Подобные документы
Damage to the structures of the central and peripheral nervous system is considered. The role of glia in the pathogenesis of spinal cord injury, ischemia, neuropathic pain and neurodegenerative diseases is described. Destructive mechanisms are described.
статья, добавлен 18.08.2022In vitro antiproliferative activity. Cell Culture conditions. In vitro determination of antioxidant activity. The cytotoxic activity of these compounds against normal cells. Identification of side effects in other biosystems and animal experiments.
статья, добавлен 17.04.2018The main functions of the liver are synthesis and regulation of lipid metabolism. Metabolic activity in the liver during pregnancy, causing changes in lipid levels in the body. Liver damage, its negative effect on lipid metabolism in pregnant women.
статья, добавлен 02.03.2021Transformation and potential tumorigenesis. Cell cycle control proteins. Oncogenic viruses: RNA or DNA. Amino acid sequence similarities in Rb binding site, kaposi’s sarcoma. Statistics of death due to apoptosis. Main changes in telomerase activity.
презентация, добавлен 11.12.2014Immunosuppressive therapy regiments. Analysis of the clinical use of mTOR inhibitors has provided evidence of comparative frequency rate of wound complications and terms of surgical wound healing in the treatment with everolimus and routine therapy.
статья, добавлен 24.02.2016The studying the opinion of the patients with respect to the offered hygienic and living conditions in some clinics of the largest hospital in Southern Bulgaria. The important role of this factor in the competitive quality of the health process.
статья, добавлен 17.04.2018Investigation of the chronic heart failure and type 2 diabetes mellitus, which are closely inter-related conditions through different pathological mechanisms. Characteristic features of the platelets abnormalities according to glycemic control status.
статья, добавлен 24.02.2016Results of evaluation of the concentration of advanced oxidation protein products in the urine of 50 children with various types of primary glomerulonephritis. Evaluation of degree of protein-mediated oxidative damage in patients with glomerulonephritis.
статья, добавлен 19.04.2018Study of forms of damage to the esophagus in gastroesophageal reflux disorder: etiology and pathogenesis, clinical symptoms. Current treatment standards for GERD. The study of non-traditional forms of treatment: acupuncture, herbal medicine, diet.
статья, добавлен 03.03.2020Disturbances of minerals calcium metabolism – calcinosis. Disturbances of copper metabolism. Disturbances of potassium metabolism. Stone formation. Causes and mechanisms of stone formation. Types of stones. Effects (consequences) of stone formation.
презентация, добавлен 12.04.2017Methods for the detection of gastroesophageal reflux and association of symptoms in children. Commercial pH registration systems. Interpretation by experts of the multichannel intraluminal impedance of the esophagus. Antireflux therapy with inhibitors.
статья, добавлен 22.03.2020Anoral and maxillo-facial surgeon, an endodontist and a general dental practitioner viewed the radiograph independently under standard conditions. Orthograde root-canal treatment for endodontic problems. Orthograde nonsurgical root-canal treatment.
автореферат, добавлен 29.03.2013Concept and general characteristics of bronchitis, their classification and types of conditions. The structure of the bronchi and the reasons for their inflammation. Etiology and pathogenesis of the disease, approaches to its diagnosis and treatment.
презентация, добавлен 27.02.2016The methodology for assessing the risks of professional burnout was used to justify the role of psychophysiological indicators in determining pre-pathological conditions in workers of certain professions. Risks of developing burnout by frequency.
статья, добавлен 09.08.2023Treatment of pathological uterine bleeding in peri- and postmenopausal women with metabolic syndrome and genital prolapse. Dependence of rational treatment of patients with comorbid pathology on the age of the patient and the degree of genital prolapse.
статья, добавлен 27.12.2023The true mechanisms of regulation of implantation and development of endometrioid heterotopias. Analysis of the treatment of clinically inactive endometriosis which is more common in pelvic peritoneal lesions, ectocervical and extracervical localisation.
статья, добавлен 20.03.2024The epidemiological technique as the set of methods intended for studying of the reasons, conditions of occurrence and distribution of illnesses and other conditions in population of people. Clinical epidemiology and social aspects of medical aid.
статья, добавлен 17.10.2016Studies of the characteristics of serum albumin in rats with different predicted levels of resistance to emotional stress in control conditions and in conditions of experimental emotional stress. The effects of peptides the resistance of animals.
статья, добавлен 10.03.2014Treatment of exposures. Mechanisms in wound healing of pulpal tissue. Direct capping and partial pulpotomy. Reparative dentinogenesis: stem cells. Tissue injury leads to alterations in gene expression. Growth factors. The choice of material recovery.
статья, добавлен 10.12.2013Correction of redox metabolism based on the parameters of oxidative modification of proteins, the degree of their catabolic reaction and data on the lipid peroxidation in cancer patients with multiple organ resections on the gastrointestinal tract.
статья, добавлен 18.04.2022With the purpose of increase of efficiency of treatment of patients with diabetes studying the possibility of introducing Zinkit (Woerwag Pharma, Germany) in a comprehensive program of treatment for glycemic control in patients when reducing hba1c.
статья, добавлен 01.12.2017Generalization of the results of the implemented studies and definition of a strategy for further research in the direction of preventing the development of occupational cancer in Ukraine. Conditions for reforming the national health and safety system.
статья, добавлен 28.12.2017The state of functioning of the innovation ecosystem in the conditions of a pandemic. The experience of reorganization of highly efficient innovation ecosystems during the crisis, which contributed to the achievement of optimal conditions for functioning.
статья, добавлен 14.02.2022The prevalence of blood reflux in patients with varicose veins of the lower extremities in the distal parts of the large saphenous vein. Its removal within the pathological reflux. Prevention of damage to lymphatic vessels and skin sensory nerves.
статья, добавлен 29.07.2018The aim of the work to study the characteristics of the state of health of pupils of senior classes of a modern school and the characteristics of its connection with medical and social indicators of the conditions of stay and lifestyle of girls and boys.
статья, добавлен 17.06.2024