Effect of memantine on calcium signaling in hippocampal neurons cultured with Р-amyloid
Alzheimer's disease (AD) is a type of dementia with accumulation of P-amyloid plaques and neurofibrillary tangles in the brain. Simulation of AD in a culture of rat hippocampal neurons to test the effect of memantine on calcium signaling in neurons.
Подобные документы
A pilot study of simultaneous DC potential and total slow of electrical activity changes during modeling at hyper- and hypoventilation of the human brain. Results of experiment with context the qualitatively different functional states of brain cells.
статья, добавлен 27.09.2013The increase secretory activity of mast cells in the mesentery and subcutaneous fat of rats. Intraperitoneal injection of Semax and prolyl-glycyl-proline. Secretory activity of mast cells in unstressed animals. The stabilizing effect of peptides.
статья, добавлен 10.03.2014Prevalence of Heart Disease, of Stroke, of hypercholestrolemia. Heart Disease case(over 12 years) combine other chronic disease. Combine risk behaviors. Establishing a comprehensive prevention and control system. The promote healthy lifestyles.
презентация, добавлен 06.04.2015Characteristics of evaluating the effectiveness of proton pump inhibitor therapy to determine whether patients have gastroesophageal reflux disease. Feature of endoscopy assessment, wireless esophageal pH and monitoring of the association of symptoms.
статья, добавлен 24.05.2020Highlights the scientific foundations that link the two-way pathophysiological mechanisms of the development of depression with the worsening of type 2 diabetes and coronary heart disease, congestive heart failure, and an increase in cardiovascular risk.
статья, добавлен 28.12.2023Study of the etiology and pathogenesis of Parkinson's disease. Critical review of available international data on the participation of inflammatory processes in the etiopathogenesis of the disease in the context of the results of our own research.
статья, добавлен 14.03.2022The place and importance of the problem of biliary system in the complex Hyper-endemic disease. Medical statistics number of patients with gallstone disease in the last ten years. Consideration of methods the therapeutic treatment of this disease.
статья, добавлен 24.02.2016Detailed assessment of tumor necrosis factor-α and interleukin-6 levels in infants and children with congenital heart disease. The importance of cytokines in the pathophysiology of congenital heart defects and their effect on the growth of patients.
статья, добавлен 25.06.2024Pathogenesis and clinical manifestations of rickets. Description of calcium-deficient rickets with secondarily elevated parathyroid hormone levels and phosphate-deficient rickets. Place of vitamin D deficiency in the mechanisms of its development.
презентация, добавлен 21.12.2014The role of glucose in the proliferative activity of tumor cells. Analysis of the microenvironment preceding the transition of tumor cells from an adhesive to a non-adhesive state. Effect of glucose on metabolic plasticity of Lewis lung carcinoma cells.
статья, добавлен 20.03.2024The general rules for healthy eating. Eat a variety of fresh fruits and vegetables, whole-grain pasta, rice, breads, and cereals, certified organic foods. Eat natural fats. Eat several good sources of calcium. Avoid processed and additive-rich foods.
реферат, добавлен 23.10.2013Pulpitis and apical periodontitis. Microbial ecology of the endodontium. The concept of infected and noninfected roots. Treatment of endodontic infection. Principles of and rationale for irrigation. Calcium hydroxide: indications and forms of application.
статья, добавлен 10.12.2013The comparative analysis of protocols of medical care for patients with brain injuries. The ability of Ukrainian producers to provide the necessary level of visualization of medical care in the treatment of traumatic brain injury in military men.
статья, добавлен 29.01.2016- 89. State of neurotransmitters (glutamate and gamma-aminobutyric acid) in patients with Wilson’s disease
Study inhibitory and excitatory neurotransmitters in patients with Wilson's disease. The contents in the blood serum of the neurotransmitter glutamate and the inhibitory neurotransmitter gamma-aminobutyric acid. Over-stimulation of the brain structures.
статья, добавлен 13.10.2016 Study the effect of EMAP II, IFN- 2b and its medicinal preparations on the amount of O6-methylguanine-DNA methyltransferase (MGMT) protein in human cells in vitro. The effect of medicinal preparations. Changes in the methyltransferase gene expression.
статья, добавлен 29.01.2017Research and analysis of using an efficient deep learning-based neural network to perform fully automatic brain region segmentation on T2*-weighted magnetic resonance images with abnormal brain anatomy. Peculiarities of neural network architecture.
статья, добавлен 26.04.2023- 92. Cerebrovascular insufficiency and diabetic encephalopathy in patients with type 2 diabetes mellitus
Features of the cognitive structure of dysfunction in patients with type 2 diabetes. Features of the diabetic encephalopathy: impaired memory, verbal fluency, orientation. The relationship of cognitive disorders with the duration of the disease.
статья, добавлен 30.01.2016 Crown-root fractures difficult to trea have a bad prognosis. Replantation with tooth rotation consist of extraction, rotation and replantation, thus restoring the biological space. Features treating inflammatory resorption with calcium hydroxide.
статья, добавлен 10.12.2013Stem cells application in neural system injuries. The determination of the level of tissue damage in hippocampus after in vitro model of ischemia and to investigate the effect of bone marrow MMSСs in non-contact co-culture with ischemic neural tissue.
статья, добавлен 28.02.2016Reduction of circulating endothelial progenitor cells as robust biomarkers for prediction of cardiovascular outcomes. Influence of angiotensin II receptor blocker valsartan EPCs in patients with ischemic chronic heart failure, type two diabetes mellitus.
статья, добавлен 27.08.2016Study of clinical manifestation of gastric ulcer disease. Symptoms of gastric ulcer disease. Comparing duodenal and gastric ulcers. Symptoms of duodenal ulcer disease. Ulcer with recent bleed. Gastric outlet obstruction. Elective surgical therapy.
презентация, добавлен 16.05.2017The study to evaluate 6 month treatment by renin-angiotensin system inhibitor and dihydropyridine calcium channel blocker ± indapamide on the variability of brachial and central arterial pressure, elastic properties of the arteries and cardiac structure.
статья, добавлен 23.02.2021Assessment of mild traumatic brain injury, posttraumatic stress disorder, and polytrauma conditions: burden of adversity hypothesis. Screening for post-traumatic stress disorder in a civilian emergency department population with traumatic brain injury.
статья, добавлен 16.11.2020Modern approaches to the development of an optimal microenvironment for in vitro models of BBB (blood-brain barrier), NVE (neurovascular unit) and NN (neurogenic niches). Particular attention is paid to the prospects of neuroengineering and bioprinting.
статья, добавлен 14.04.2022The studies of the effects of the ACTH(4–10) analog Semax (MEHFPGP) on the behavior of white rats with lesions to the brain dopaminergic system induced by the neurotoxin MPTP. The neurotrophic action of the peptide. Induced lesions of the brain.
статья, добавлен 10.03.2014