Mining the cryptic specialized metabolome of Streptomyces cyanogenus s136
Review of the Streptomyces cyanogenus S136 strain as a producer of the landomycin family of antibiotics, among which landomycin A is synthesized. Study of the transcriptome of the S136 strain. Use of regulatory genes to activate cryptic clusters.
Подобные документы
Vitamin D as a member of the family of fat-soluble secosteroids obtained through diet or direct sunlight that converts 7-hydroxycholesterol to a precursor. Its role in bone remodeling, calcium regulation. Functions of vitamin in kidney diseases.
статья, добавлен 04.09.2024This study demonstrated that decreased MNBI in the proximal esophagus can not only identify LPR patients but also predict patients’ symptom outcomes. Distal reflux parameters comparison. Proton pump inhibitors treatment. Distal reflux parameters.
статья, добавлен 17.05.2020Development and testing of the technology of obtaining dry extract of stems of hops. Study of the effect of temperature parameters of the evaporation and drying of liquid extract hops on branilovic quantitative content of flavonoids in dry extract.
статья, добавлен 26.07.2016Optimization of medical treatment and physiological stabilization during assistance to the wounded. Specialized assistance during evacuation and initial surgical stabilization of cranial trauma. Intensive therapy at the stage of aeromedical evacuation.
статья, добавлен 19.03.2024Electrophoretic analys of globulin storage proteins in the seeds of 46 lentil accessions introduced from ICARDA was carried out. The aim of the work was to identify, certification, study the genetic diversity of lentil genotypes, genetic diversity index.
статья, добавлен 03.09.2024Studies on the antistress protective actions of peptides of the glyproline family: Pro-Gly-Pro, Pro-Gly, and Gly-Pro. Typical changes in the behavioral activity of rats in the elevated cross maze. Providing evidence of a significant increase in anxiety.
статья, добавлен 10.03.2014Medical documentation tracks the patient's path during the diagnostic and treatment process. Patient relationship-health services-regulatory requirements. The documents created in hospital: normative and internally institutional, general and specific.
статья, добавлен 23.02.2021Studying the notion of testosterone (belongs to a family of androgens) as a hormone that stimulates sexual development in male human beings. Consideration of opinion Eugene Shippen and William Fryer for researched topic in book "Testosterone syndrome".
реферат, добавлен 30.06.2014The purpose of study was the reaction of the circulatory system for spontaneous breath in patients with normotensive type of reaction to dosed physical load. Was used a modern method of spiroarteriocardiorhytmography study of the cardiorespiratory system.
статья, добавлен 27.09.2018The aim of study was to compare the survival rates and the complication rates of established methods of indirect cast posts and cores and direct posts and composite cores 5 years within a retrospective study of patients who received fixed restorations.
статья, добавлен 05.03.2013The gasdermin family (GSDMs) contains a group of uncharacterized proteins that form membrane pores and serve as a major substrate for inflammatory caspases and the execution of pyroptosis, which is recognized as a novel type of programmed cell death.
статья, добавлен 03.09.2024Peppermint as a herb, a species of mint family Lamiaceae. Culture by hybridization of wild species of mint— water and garden. The traditional use of the flower for gastrointestinal disorders, nausea and colds, headache and cramps. Tea is consumed in.
презентация, добавлен 27.09.2014The pharmacognostic study of the composition and the quantitative content of free coumarins in the overground parts of the raw material of the representative of Medicago L. genus – Medicago falcate L. subsp. romanica (Prodan) O. Schwаrz & Klink.
статья, добавлен 29.01.2016The problem of assessing the participation of autonomic support of mental activity in terms of heart rate. Investigation of the level of activation of regulatory mechanisms of heart rhythm during the increase of the speed of verbal, image processing.
статья, добавлен 18.12.2020Physiotherapy of patients with lumbosacral osteochondrosis is considered, which is an urgent problem of clinical neurology, family medicine and kinesiotherapy. Dorsalgia is a striking symptom of this disease, it is observed in 40-80% of the population.
статья, добавлен 29.10.2020The consequences of the use of psychoactive substances - diseases that lead to mental, somatic and social decompensation. Diagnostics, treatment and rehabilitation of surfactant users. Fundamentals of drug addiction and psychotherapeutic assistance.
статья, добавлен 17.11.2020Formation of a research system for optimizing pharmaceutical care for children with ENT diseases in outpatient polyclinic institutions based on a systemic approach. Assessment of effectiveness of drug consumption, legislative and regulatory documents.
статья, добавлен 20.07.2024To evaluate the pharmacokinetic and pharmacodynamic characteristics of YH1885, a novel proton pump inhibitor, a single-blind, randomized, placebo-controlled, dose-rising, parallel-group study was conducted in forty six healthy volunteers. Dose study.
статья, добавлен 30.03.2020Review the model of osteoarthritis in the rat line Wistar. Effect of the one-time injection of CH3COOI acid on the knee joint. Physiological, histological, cytological and radiological methods for diagnosing changes of the bones of the skeleton in human.
статья, добавлен 02.12.2017The rationale and techniques for treatment of the non-vital immature tooth. The treatment of choice for necrotic teeth is apexification, which is induction of apical closure to produce more favorable conditions for conventional root canal filling.
статья, добавлен 05.03.2013To study the characteristics of physical development, depending on the severity of the course and measures of secondary prevention in patients with bronchial asthma. In this study included 100 children with bronchial asthma in aged 10 to 16 years.
статья, добавлен 10.02.2021Analysis of Zaytsev's personal qualities, as well as the facts of his becoming a person, a talented surgeon, a professional in his business. The review of the directions of his medical, scientific and pedagogical activity, contribution made to medicine.
статья, добавлен 25.12.2016Natural products can be used as novel therapeutic interventions with improved pharmacological properties targeting tumor cells. Consideration of phytomedicines for adjuvant therapy, ability to diminish adverse effects of chemotherapy in cancer patients.
статья, добавлен 03.09.2024Definition, the basic physical and chemical properties, advantages and possibilities of application of nano-emulsions in the pharmaceutical, cosmetic, food, chemical industries. Characteristics of the methods and mechanisms for obtaining nanoemulsions.
статья, добавлен 26.07.2016The percent time pH is less than 4 in the distal esophagus, termed the acid exposure time - the most relevant and reliable parameter on ambulatory reflux monitoring. Heartburn like a separate entity that warrants a multimodal management distinct.
статья, добавлен 01.04.2020