Functional and mutational analysis of the identification of py-binding residues ON PDE6
Photoreceptor cGMP phosphodiesterase is an effector enzyme in the G-protein mediated visual transduction cascade. To study the mechanism of PDE6 catalytic activity inhibition by Py chimeric proteins PDE6a/PDE5 were created. The catalytic properties.
Подобные документы
The study of cell-mediated immunity depending on the power and time of exposure to electromagnetic radiation of radio frequency on experimental animals. Depression of cellular immunity and increase with increasing duration of the electromagnetic impact.
статья, добавлен 30.01.2016Anti-inflammatory properties of SnCl4 with benzaldehyde and 4-bromobenzaldehyde salicyloyl hydrazones the were studied in the rats using models on carrageenan and formalin-induced inflammation of paw. The anti-inflammatory activity in both models.
статья, добавлен 21.10.2021Over the past twenty years, ionic liquids have attracted the attention of the chemical and biological communities due to their extraordinary physical and chemical properties. Currently, these compounds are widely used in various fields of science.
статья, добавлен 20.07.2024An electroencephalogram signal that is produced by neurons in the cerebral cortex. The issue of wireless transmission of EEG signals and the subsequent application of wavelet transform for time-frequency analysis of the electrical signal of the brain.
статья, добавлен 29.08.2021Analysis of ways to ensure public health protection of individual citizens. Methods of access of seriously ill patients to medicines created using the latest technologies, but which are not yet allowed in the state. Signs of the patient's special needs.
статья, добавлен 02.10.2024The study of the etiology, pathogenesis, clinical symptoms, characteristics and diagnostic methods of treatment of irritable bowel syndrome is a functional disorder of the bowels characterized by chronic abdominal pain, discomfort, bloating and colon.
презентация, добавлен 06.02.2016Research of the concept of prevention, correction of functional disorders of the musculoskeletal system of mature persons in the process of physical education. Individual features of the state of the biogeometric profile of posture, theoretical component.
статья, добавлен 01.11.2021- 108. Methodical approach to the study of intersystem interaction of human cardiovascular system and brain
Electroencephalography like one of the main tools that allow to investigate brain and heart function without resorting radical surgical methods. Characteristics of the role of the functional mobility in psycho-physiological functions of a person.
статья, добавлен 29.10.2020 Prevention and treatment of viral infections. Research of antibacterial, anti-inflammatory and antifungal properties of coordination compounds of biometals with bioligands. Features of the structural organization of chelates of the "phage-host" model.
статья, добавлен 20.07.2024Principles for the distribution of frequencies of genotypes compared with the control group at the expense of Pro / Pro genotype frequencies were found in the study group (p <0.05). Evaluation of the relative risk of carrying an odds ratio (OR) values.
статья, добавлен 28.08.2016The study the survival time of root canal fillings and the use of Kaplan-Meier analysis. Process control radiographs and value log-rank test. Cumulative evaluate root canal fillings. The factors baseline periapical condition, length, condensation.
статья, добавлен 30.03.2013Identification of the effect of kinetzitherapeutic agents and methods on improving the health status of patients with Down syndrome. Study of the features of the disease caused by the presence of an additional chromosome in the human genetic structure.
статья, добавлен 25.11.2021- 113. Esophageal Disorders
Familiarity with functional disorders of the esophagus. Consideration of the causes of damage to the intestines of the mucous membrane. Analysis of the interaction of esophageal hypersensitivity and acid exposure in the spectrum of reflux symptoms.
статья, добавлен 03.03.2020 A comprehensive study of the pharmacological properties of soft drugs. Methods of regulation of drugs for the treatment of wounds. The stability gel when the temperature changes. Structural-mechanical and rheological characteristics of the product.
статья, добавлен 29.01.2016Microscopic fungi including yeasts are important part of human microbiota. The molecular genetic identification of human sputum yeast isolate MF22_1, belonging to Candida spp., by using multiple genetic markers including ribosomal operon regions.
статья, добавлен 10.06.2023Development of a therapeutic and diagnostic algorithm for the blockade of natural fistulas of acute rhinosinocytes. Early diagnosis, study of the etiopathogenetic influence on the main factors in the occurrence and development of these complications.
статья, добавлен 17.02.2023Characteristic and research features of the liver which is located in the right upper quadrant of the abdomen, just below the diaphragm. Identification and analysis of the difference in child liver. Familiarization with the basic functions of liver.
эссе, добавлен 13.09.2016Prevalence of diabetes according to the World Health Organization. Research proinflammatory cytokine and its role in disease pathogenesis. Analysis of the results of pharmacological screening hypoglycemic antagonist properties raleykina IL-1 receptors.
статья, добавлен 24.02.2016The obtained data illustrate the improvement of the indicators of functional tests of the spine against the background of anti-inflammatory therapy, and in the group of patients receiving PRP-therapy demonstrated a more stable positive dynamics.
статья, добавлен 26.01.2021Investigation of the mechanism of dental plaque formation. Study of the impact of mental disorders and stress on the development and course of human periodontal diseases. Engineering of prevention schemes and rational pharmacotherapy in modern dentistry.
статья, добавлен 19.03.2024The choice of substances as the main active substances for manufacturing of medicinal immunomodulating preparation in the form of granules. The study of physico-chemical, method of granulating and farmakodinamiceski properties of granules with pollen.
статья, добавлен 26.07.2016Identication and assessment of risks arising in the process of manufacture of extraction herbal medicines. Technological process of manufacture of multicomponent tinctures and liquid extracts, in particular "Climased". Risk analysis of production.
статья, добавлен 29.10.2016The mechanism of action of ethanol on the CNS. Alcohol as stimulating the balance of the braking effect in the brain, resulting in anxiolytic effects, ataxia, and sedation. Long term sexual effects of alcohol. Erectile disorders and dysfunction in men.
эссе, добавлен 06.08.2014The study of the level of physical activity, dairy products and calcium intake by students of Islamic Azad University of Damavand in Iran. Factors affecting the health of the skeletal system. Modern methods of preventing osteoporosis in female students.
статья, добавлен 05.12.2018Research of reactive properties of substituted 6,9-dichloracridines and its acid-base properties. Characteristic of the influence of the nature and position of substituents in the heterocycle upon the strength of the corresponding associated acids.
статья, добавлен 24.02.2016