Development and investigation of emulsion form for antiepileptic drug carbamazepine
Obtain a carbamazepine nanoemulsion for intravenous administration. The nanoemulsions were evaluated concerning droplet size, zeta potential and drug content. Preliminary studies of anticonvulsant activity for resulting formulation were carried out.
Подобные документы
Alkylation of potassium 9-R1-10-R2-3-R-2-oxo-2Н-[1,2,4]triazino[2,3-с]quinazolin-6-thiolates by N-cycloalkyl-(cycloalkylaryl-)-2-chloracetamides. Analizes of indicators of the antiviral activity of compounds 3.2 and 3.14 against influenza type A H3N2.
статья, добавлен 29.01.2016Synthesis, selection of new catalytic systems based on vanadium, molybdenum, zirconium, cobalt, iron for the conversion of methanol to formaldehyde and other valuable compounds, determination of their activity and kinetic regularities of the process.
статья, добавлен 12.12.2024The pattern of pulse flows of cortical neurons is a complicated phenomenon. Apart from properties of single neurons, action of a system of neuronal circuits reflected in organisation of spike bursts. Characteristics of burst activity before irradiation.
статья, добавлен 26.07.2013The technology of obtaining and comparative tests of the medical enterosorbents, activated coal and lignin enterosorbents. High activity lignin enterosorbents at the treatment of lacto-dependent diarrhoea. Physical-chemical features of enterosorbents.
статья, добавлен 02.04.2014Method of syntesis of novel N-substituted 3-(aminosulfonyl)-2H-1-benzopyran-2-one in the Knoevenagel condensation conditions. Studing the biological activity of derivatives against protozoan and helminth parasites, active against Onchocerca lienalis.
статья, добавлен 19.02.2014Ion exchange separation of sulfate and chloride with highbasic anionite Сl-species at regeneration solutions treatment for their reiterative use, followed with solutions’ desalination at reverse osmosis plant, and resulting concentrates’ demineralization.
статья, добавлен 29.11.2016Synthesis of a methacrylic azomonomers based on para-aminoacetanilide to obtain functionalized polymers for orientation of liquid crystals. The kinetics of polymerization of synthesized azomonomers. Constants of thermo-induced radical polymerization.
статья, добавлен 21.12.2016Depth profiles of the near-surface region and chemical composition for amorphous films deposited from Ge33As12Se55 bulk glasses and their changes resulting ageing under ambient conditions have been studied by the methods of Auger electron spectroscopy.
автореферат, добавлен 02.04.2014Theoretical modeling in the sphere of computational modeling of protein folding. The analysis of spectroscopic methods to obtain information, taking into account the kinetics at conceptual and practical level. Basic physical stabilisation force.
учебное пособие, добавлен 05.07.2013The use of a sorbent to study the preliminary concentration of V (V) ions in the liquid phase. Establishment of optimal conditions for sorption. Influence of the concentration of metal ions and the time of reaching chemical equilibrium on sorption.
статья, добавлен 27.02.2021The concept and essence of polyaniline. Research of mats made of polylactic acid and polyaniline, their production by electroforming. Identification of the advantages of using a scanning electron microscope. Electrical conductivity of the resulting mats.
статья, добавлен 15.01.2021Dependence of the size of tannin nanocapsules on the nature of the shell. Considering the nanoparticle in guar gum having the lowest average value and the shell consisting of sodium alginate having the highest value. Properties of nanostructured tannin.
статья, добавлен 21.05.2023Purines Fused to Six-Membered Heterocycles. Pyrido-, pyridazino-, pyrimido-, pyrazino-, oxazino-, thiazino-, triazino-purines. Purines Fused to Seven- and Eight-Membered Heterocycles. Oxdiazocino- and Thiadiazocino-Purines Efforts to obtain compounds.
статья, добавлен 05.03.2013The article discusses solutions to the problem of recycling wood waste and its use as a raw material for the production of new high-quality materials for industries. The purpose is to obtain composite materials containing wood waste and epoxy resin.
статья, добавлен 08.01.2021Study of swelling kinetics as compared to solvents of various nature (water in various pH, ethanol, toluene) was carried out. IR comparative spectra were obtained for different composites. High anti-bacterial action of the synthesized nanocomposites.
статья, добавлен 30.07.2016Influence of synthesis conditions on ceria particles size. Anticorrosion properties of modified carbon nanotubes. Realization the synthesis in aqueous solution at room temperature that reduces the cost of the preparation procedure of nanosized ceria.
статья, добавлен 04.04.2014The desorption non-isothermal kinetics of preliminary adsorbed Cl, Br, and I-containing volatile halocarbons from the surface of surrogates for atmospheric solid aerosols (fumed silica and alumina, silica gel and H-mordenite) was studied by TPD MS.
статья, добавлен 03.04.2014Study of influence of amino acids on the hydroxyapatite formation. Study of mineral obtained by transmission electron microscopy and powder X-ray diffraction. Analysis of the phase composition, crystal size and lattice microstrains of calcium phosphate.
статья, добавлен 23.12.2016The one-step procedure of simultaneous preparation of polyacrylonitrile-based carbon support and Fe-Pd bimetallic nanoparticles. The effect of synthesis conditions on the metal-carbon nanocomposite structural characteristics. The crystallite size.
статья, добавлен 27.08.2020Effect of the segregation of electrically active dopants. Diffusion theory of the hole current. Polysilicon emitter contacts and its dependence on dopant concentration. Hole mobility versus grain size for two values of the total dopant concentration.
статья, добавлен 29.04.2017Crystalline and electronic structures of nanoalumina alone and in different mixtures with nanosilica. X-ray diffraction and ultrasoft X-ray emission spectroscopy. Pore size distributions calculated. Resalts of the OKa emission bands of alumina in samples.
статья, добавлен 20.03.2016The novel approach to chemical design of carbon-coated Al2O3 nanoparticles with an average particle size of 8-10 nm was developed. Carbon coating was synthesised by modification of fumed alumina support with 4,4-methylenebis and its subsequent pyrolysis.
автореферат, добавлен 02.04.2014To study antimicrobial properties of the synthesized surfactants, the method of consequent dilution was used. The experiments were carried out in the test tubes contained a surfactant at different concentrations and 1 ml of the physiological solution.
статья, добавлен 03.03.2021Determination of aminoglycoside antibiotics (gentamicin, kanamycin, amikacin, neomycin) in food products by the method of polarization fluorescent immunoassay. Influence of the size of a fluorescent molecule on the degree of polarization of fluorescence.
статья, добавлен 10.05.2018Reviews on "Heterocyclic Compounds" on aspects such as synthesis, reactionmechanisms, structure complexity, properties, reactivity, stability, fundamental and theoretical studies, biology, biomedical, pharmacology, applications in material sciences.
материалы конференции, добавлен 05.03.2013