Features of the 8-oxo-7,8-dihydro-2'-dGTP behavior in active site of human DNA-polymerase В: structural investigation in silico
Mutagenic potential of oxidized forms of nitrogen bases. The effectiveness of the inclusion of 8-oxo-DG in the growing DNA. The behavior of the molecule 8-oxo-DSTF in the migration trajectories. The transition of cells from normal state to cell death.
Подобные документы
Study of polyhydroxyalkanoates, which are aliphatic polyesters. The process of synthesis and accumulation of aliphatic polyesters in bacterial cells. Obtaining a low molecular weight copolymer with a high content of monomers in bacterial cells.
статья, добавлен 13.04.2022Relationships between the antioxidant status and the structural features of some representatives of the calciphytic flora. Evaluation of redox metabolism by leaf hydration, content of photosynthetic pigments, phenolic compounds, water-soluble proteins.
статья, добавлен 14.04.2022Potential of living organisms. Stages of the formation of the biosphere in the context of closure and possible approaches to resolving the paradox. The effect of stoichiometric constraints on the formation of closed material flow in simple ecosystems.
статья, добавлен 13.04.2022Amyloid fibrils, which include PAP248-286 and PAP85-120 fragments of prostatic acid phosphatase. Studying the features of oligomers of SEVI-forming peptides by constructing their molecular models that have proven their effectiveness in the study of SEVI.
статья, добавлен 03.03.2023Analysis the morphological, functional states of neuromuscular junctions of drosophila larvae expressing synuclein wild type, its mutant forms and induces morphological changes in NMJs, reducing the number of mitochondria in axon presynaptic terminals.
статья, добавлен 27.07.2016The paper describes the change in perspective in the composition of the A. messeae taxonomic unit. Initially, based on the disequilibrium ofnatural populations, the species was differentiated into A and B forms using chromosomal inversions as markers.
статья, добавлен 03.08.2021The technology of soil preparation and sowing of seeds, to increase the productivity of growing biomass of rod-shaped millet for the production of solid biofuels in the Western Forest-Steppe, taking into account the characteristics of plant development.
статья, добавлен 14.07.2022This article describes the chemical structure of the antimicrobial proteins presently and their presence in different families of Anura. The main aim of the work is to show the variability of these substances and study of their pharmaceutical potential.
статья, добавлен 20.09.2020The effects of contamination and prolonged warming. Molecular response to stress and toxicity of the environment in the bivalve mollusc Anodonta anatina. Indices of inter-seasonal variability for oxidized glutathione and metallothionein-sensitive thiols.
статья, добавлен 28.01.2016Investigation of the unique plant communities of Ordubadsky district. Classification of structures of the mountain-xerophytic and steppe flora of the region. Identification of the taxonomic composition and classes of tree species of the Rosaceae family.
статья, добавлен 10.10.2024Mechanisms for the identification of yeast cultures by polymerase chain reaction. Morphological and biochemical properties of the culture. The specificity of fermentation a carbohydrates and hydrogen sulfide formation from different grape varieties.
статья, добавлен 13.09.2016Technology using video and acoustic equipment using various scenarios of interaction between a human and a dolphin beluga. The use of a sequence of packets of ultrashort broadband pulses of various durations. Acoustic characterization of animal signals.
статья, добавлен 11.11.2018The essence of the concept of the energy mechanism of the functioning of the human body at the micro-and macro-level of energy - mass compaction. Automating the diagnosis and treatment of diseases through the control signals of quantum computers.
статья, добавлен 19.02.2021The frequency of GSTT1 and GSTM1 gene deletion polymorphism was determined in a casecontrol study of fullterm Ukrainian newborns including patients with perinatal asphyxia. Multiplex polymerase chain reaction was used for genotyping 245 fullterm newborns.
статья, добавлен 11.11.2012- 65. Andreas Vesalius
The activities of the founder of scientific anatomy Andreas Visalia. The scientific description of all organs, systems in the book of the scientist "On the structure of the human body". Illustrations parts of the human body as an achievement of science.
презентация, добавлен 31.03.2015 Роль микроорганизмов в метаболических процессах различных экосистем. Выявление микроорганизмов и метаболических путей, ответственных за деградацию полисахаридов бурых водорослей. Значение исследования для понимания глобального метаболизма углеводов.
статья, добавлен 11.07.2018Properties of cognitive processes characteristic of humans, their possible prerequisites for the example of other biological species. Human language as a species-specific ability of the brain, a means of communication, an important tool of cognition.
статья, добавлен 03.06.2021Розробка методу обчислення точкових атомних зарядів органічних сполук. Релаксація електронегативностей за Кіргофом та проведення його параметризації. Ідентифікація інгібіторів протеїнкінази. Створення комплексу для оцінки молекулярної спорідненості.
автореферат, добавлен 26.09.2015An introduction to basic principles of molecular genetics pertaining to the genome project. Mapping and Sequencing the Human Genome. Model Organism Research. Informatics: Collection and Storing Data and Interpretation. Impact of the Human Genome Project.
учебное пособие, добавлен 25.11.2013Study of the influence of nitrogen and carbon sources on the synthesis of enzymes. Carrying out a bifractor experiment to determine the optimum concentrations of ammonium sulfate and arabinose in a nutrient medium, which increase the elastolytic activity.
статья, добавлен 28.09.2016- 71. History of studying chronorithms in the regulation of physiological functions of the human organism
Chronorhythmic regulation of physiological functions and the effect of desynchronosis on the human body, The role of the pineal gland and the pineal hormone melatonin in the daily and seasonal rhythm and in the inhibition of sleep-activity regimens.
статья, добавлен 05.02.2023 Дослідження та аналіз особливостей модифікації методу філогенетичного футпринтингу для відбору еволюційно-консервативних сайтів зв’язування транскрипційних факторів у еукаріот. Визначення та характеристика можливості пошуку у масштабі всього геному.
автореферат, добавлен 27.07.2015Features of physiological and biochemical structure of rats. Study of anatomic and histological features of ventilation of diaphragm department of easy rats. Pool of pulmonary veins and indexes of disease of cages of mucous membrane of bronchial tubes.
презентация, добавлен 08.10.2013Приготування зразків деградованої дезоксирибонуклеїнової кислоти. Визначення точності та достовірності системи 7500 PCR Real Time/Quantifiler Human. Стабільність системи, вплив інгібіторів на реакцію полімеразної ланцюгової реакції у реальному часі.
статья, добавлен 24.08.2018Since the advent of recombinant DNA technology three decades ago, thousands of eukaryotic genes have been isolated. The differential expression of these genes is critical for both normal cellular processes and abnormal processes associated with disease.
книга, добавлен 05.07.2013