Heterologous cross-expression of oxygenase and glycosyltransferase genes in streptomycetes, producing angucyclic antibiotics
The heterologous expression of oxygenase and glycosyltransferase genes, changes in antibiotics production, resulting from post-PKS synthase tailoring gene expression in streptomycete strains. The potential of genes for generation of bioactive metabolite.
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Since the advent of recombinant DNA technology three decades ago, thousands of eukaryotic genes have been isolated. The differential expression of these genes is critical for both normal cellular processes and abnormal processes associated with disease.
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