Fact or fancy: Does the high level of PKC-delta gene expression contribute to potassium channels malfunction at arterial hypertension and diabetes
Identify of weather PKC-d gene silencing using siRNAs restores K+ channels function in VSM damaged following arterial hypertension and diabetic development. Induction of diabetes. Total mRNA isolation and real time (RT)-polymerase chain reaction.
Подобные документы
The action of luteolin in the treatment of renovascular hypertension, lowering blood pressure, deremodeling of baroreflex sensitivity, renal and cardiac hypertrophy. Analysis of the mechanism of pharmacological action of long-term treatment with luteolin.
статья, добавлен 28.07.2023Intracranial hypertension is the cause of mortality in patients with cranial injury. The traumatic brain injury is a public health problem. Decompressive craniectomy emerges as a treatment strategy for patients with refractory intracranial hypertension.
статья, добавлен 14.10.2016Identified risk factors should contribute to active educational and curative work among the children’s population, to prevent the development of obesity, the formation of complications from this pathology. Metabolic syndrome in children and adolescents.
статья, добавлен 03.02.2021Determine the effect of diacamph hydrochloride, an antihyperglycemic drug, on the cortisol content in the blood of animals with a combined model of diabetes mellitus and chronic stress. Analysis stress-protective properties of diacamph hydrochloride.
статья, добавлен 27.08.2016The cardiovascular system of the human. Pathway of the blood. Size, shape, location of the heart. Systemic and pulmonary circulation. Conducting system of heart. Factors affecting mean arterial pressure. Reflexes of the baroreceptor and chemoreceptor.
презентация, добавлен 05.12.2015Prevalence of diabetes according to the World Health Organization. Research proinflammatory cytokine and its role in disease pathogenesis. Analysis of the results of pharmacological screening hypoglycemic antagonist properties raleykina IL-1 receptors.
статья, добавлен 24.02.2016Studying the activation of proinflammatory processes in hypertensive patients with significant progression according to the degree of blood pressure and additional anti-inflammatory properties of candesartan after 12 weeks of medication treatment.
статья, добавлен 26.07.2016With the purpose of increase of efficiency of treatment of patients with diabetes studying the possibility of introducing Zinkit (Woerwag Pharma, Germany) in a comprehensive program of treatment for glycemic control in patients when reducing hba1c.
статья, добавлен 01.12.2017Evaluation of oral hygiene indices and periodontal indices in children with type 1 diabetes mellitus. Children with diabetes mellitus had gum bleeding both during the period of temporary bite, and the period of mixed bite. Gingival indices in children.
статья, добавлен 04.12.2023Determination of the relationship between the taurine / alanine ratio of serum heart rate variability in patients with post-infarction cardiosclerosis and type 2 diabetes mellitus. Pathogenetic mechanisms of carbohydrate metabolism disorders in patients.
статья, добавлен 17.11.2020Research, analysis of the history of medicine, which forms new ideas about the formation of blood groups. Prerequisites for the emergence of the "vegetarian" second blood group A. The homeland of the gene of the third group B. The fourth blood group AB.
статья, добавлен 20.02.2023Determination of the number of matrix ribonucleic acid genes in leukocytes in some forms of epilepsy and Parkinson's disease. Identification of new biomarkers of diseases for the development of molecular test systems suitable for clinical diagnosis.
статья, добавлен 19.04.2018Chain of the blood coagulation system. Fibrinolysis and systemic plasma proteolysis. Conditions of occurrence, causes of formation and progression of somatoform autonomic dysfunction. Activation of the hemostasis system in response to inflammation.
статья, добавлен 21.12.2016Lesions of the respiratory and cardiovascular systems. Cardio-respiratory system. The problem associated lung lesions and cardiac patients suffering from bronchial asthma. Formation of pulmonary hypertension. Violations of intracardiac hemodynamics.
статья, добавлен 28.01.2016Reduction of circulating endothelial progenitor cells as robust biomarkers for prediction of cardiovascular outcomes. Influence of angiotensin II receptor blocker valsartan EPCs in patients with ischemic chronic heart failure, type two diabetes mellitus.
статья, добавлен 27.08.2016Study the effect of EMAP II, IFN- 2b and its medicinal preparations on the amount of O6-methylguanine-DNA methyltransferase (MGMT) protein in human cells in vitro. The effect of medicinal preparations. Changes in the methyltransferase gene expression.
статья, добавлен 29.01.2017Systematic mutagenesis of all predicted gntR genes in Xan-thomonas campestris campestris reveals a GntR family transcriptional regulator controlling hypersensitive response. Lambda red-mediated genetic manipulation of antibiotic-producing streptomyces.
статья, добавлен 30.01.2016Interferon - direct antitumor factor or as a part of complex cancer treatment aimed at reducing the risk of metastatic process. Analysis of the main viral vector systems used in gene therapy. Determination of the metastatic potential of MM-4 cells.
статья, добавлен 27.03.2016The results of molecular cytogenetic studies in 60 patients with chronic lymphoproliferative neoplasms. Clonal deletions of TP 53 gene were detected in 20% of patients with CLPN: eight of 20 patients with B-cell chronic lymphocytic leukemia (B-CLL).
статья, добавлен 18.12.2023Chris Hani Baragwanath Academic Hospital (CHBAH) - the third largest hospital in the world. Activities of African Centre for Gene Technologies Philosophical Papers. The history of the creation CHBAH. Consideration of the largest hospitals in the world.
реферат, добавлен 16.09.2014The analysis of the mechanism of oxidative stress that can lead to diabetic cataract: the method for inserting a lens of cattle in culture conditions to high concentrations of glucose and protection with special antioxidants, selective chelator for iron.
статья, добавлен 07.02.2014Examination of retinal thickness in the macular region before and 1, 3, 6 months after closed subtotal vitrectomy and PRLC and PHACO in combination with closed subtotal vitrectomy and PRLC. Analysis of the frequency of DME and other manifestations of DMP.
статья, добавлен 23.02.2021Investigation of the influence of mitoKATP activation by uridine on external respiratory function under experimental pneumonia. Сharacteristics of functional state of external respiration system. Parameters of the pattern of respiration and gas exchange.
статья, добавлен 10.06.2022Analysis of carbohydrate metabolism depending on the genotype of the leptin receptor gene (Arg223Gln) in patients with coronary heart disease and obesity. Causes of lipid metabolism disorders, hyperinsulinemia and decreased tissue sensitivity to insulin.
статья, добавлен 11.12.2023Effect of extract of goutweed ordinary, tinctures goutweed ordinary and the infusion collection "Arfazetin" on the histological structure of kidneys and liver of mice with alloxan diabetes. Principle of action of drugs and effects of treatment of mice.
статья, добавлен 24.02.2016