Molecular-biological factors of risk of recurrence and metastases development in patients with ovarian cancer of the III-IV stages
Non-adjuvant polychemotherapy - technology that indicates the presence of chemo-resistant tumor cells. Molecular-biological markers of tumors - certain chromosomal and gene mutations that involved in the development, progression of malignant diseases.
Подобные документы
The relationship between pulp and periapical diseases. The stages of disease progression in tissue as a result of a stimulus or irritant that is not removed or treated. Periapical inflammation without pulp infection. Classifications of periapical diseases
статья, добавлен 10.12.2013Intercellular communication is one of the most important factors in maintaining tissue homeostasis. Correlation of intercellular interaction with human diseases, including carcinogenesis. Analysis of exosomal involvement in tumor-stromal interactions.
статья, добавлен 29.01.2017Microbiological and molecular methods used to study the microorganisms associated with endodontic infections. Endodontic infections are polymicrobial with usually from 3–12 species cultivable from either infected root canals or periradicular abscesses.
статья, добавлен 10.12.2013The methodology of creating the guidelines for the system of health technology assessment, the main stages of the informative components of the National guidelines in health technology assessment. The assessment of the organizational consequences.
статья, добавлен 29.01.2016Reports on the development of protocols of isolation of mesenchymal stem cells from umbilical cord blood and launch services of their long-term banking. Consideration of clinical trials to study the efficacy of such cells in the treatment of diseases.
статья, добавлен 28.02.2016Small animal models of osteoarthritis are suitable for preclinical investigations of OA pathogenesis: its genetic and molecular mechanisms; large animal allow to investigate biomechanical changes of the joint and to provide intraarticular interventions.
статья, добавлен 30.07.2016Comparison of the effectiveness of analgesics used in the treatment of cancer patients with complaints of pain in the emergency department. Exploring the benefits of using nonsteroidal anti-inflammatory drugs, paracetamol or opioids over other drugs.
статья, добавлен 21.03.2022Creation of an antitumor drug based on biologically active substances of wormwood. Possibility of using the drug in the complex treatment of oncological diseases. Clinical determination of living cells by fluorescence spectroscopy.
статья, добавлен 01.09.2021Indicators of incidence of malignant tumours of the female population in Russia. Number of patients in oncology dispensaries. The problem of detection of oncopathology. The level of mortality from the pathology of the organs of the reproductive system.
статья, добавлен 17.04.2018Identified risk factors should contribute to active educational and curative work among the children’s population, to prevent the development of obesity, the formation of complications from this pathology. Metabolic syndrome in children and adolescents.
статья, добавлен 03.02.2021Generalization of the results of the implemented studies and definition of a strategy for further research in the direction of preventing the development of occupational cancer in Ukraine. Conditions for reforming the national health and safety system.
статья, добавлен 28.12.2017The analysis of archival medical records of patients with treatment-resistant depression for the period from 1991 to 2010. Clinical and therapeutic indicators that allow establishing the patterns for pathomorphism of treatment resistant depression.
статья, добавлен 21.03.2016Diagnostic and clinical parameters of the symptoms of the cancer disease of the small intestine. Complications that can be caused, as a result of a cancerous tumor. Comorbidities that occur suddenly and in need of treatment by surgical intervention.
презентация, добавлен 26.02.2014The role of glucose in the proliferative activity of tumor cells. Analysis of the microenvironment preceding the transition of tumor cells from an adhesive to a non-adhesive state. Effect of glucose on metabolic plasticity of Lewis lung carcinoma cells.
статья, добавлен 20.03.2024Authors develop a technique laser recanalization of colon tumors, allowing in the conditions of intestinal obstruction to execute early antegrade decompression of digestive tracts with its fast restoration and early clinical-metabolic compensation.
статья, добавлен 28.07.2016Investigate a possible role of the polymorphisms by comparing the distribution of genotypes in the control group and in patients with type two diabetes mellitus and retinopathy. Analysis of the reasons for the increase in the frequency of heterozygotes.
статья, добавлен 23.02.2021Identify the optimal strategy to improve communication in patients with rare neurological diseases, using different models of intervention. Speech therapy used for patients. Disorders caused by rare neurological diseases. Creation of AAC technologies.
статья, добавлен 07.09.2021International studies of the clinical picture of the cognitive functioning of patients with paranoid schizophrenia in combination with cerebrovascular diseases. Principles for the development of personalized treatment methods for a patient population.
статья, добавлен 01.09.2021The concept and clinical picture of an adenoid cystic carcinoma as a rare form of a malignant tumor with epithelial origin. Justification of the choice of the scheme of its optimal treatment, surgical approach and the degree of radical tissue removal.
статья, добавлен 17.04.2018Substantiation of technological parameters of production of capsules containing herbs bedstraw. The study of the kinetics of water absorption of different compositions of powder mixtures. Development of technology of capsules, codenamed "Galiver".
статья, добавлен 24.03.2016Bradykinin receptor 2 as an attractive therapeutic agent for glioma patients. A high antiproliferative activity in the human glioblastoma cells U373. Effect of nonapeptide bradykinin antagonists on U373. BKM-570 as a potential anti-cancer agent.
статья, добавлен 27.03.2016Analysis using the standard during quantitative determination of analytes in biological fluids. The development of a series of spectrophotometric methods of quantitative determination of captopril in blood, based on the reaction with Ellman reagent.
статья, добавлен 28.09.2016Multi-disciplinary and endovascular approach to the treatment of kidney cancer. Clinical description of the operation for a male patient with intraparenchymatous kidney cancer and a postoperative course complicated by a rare vascular pathology.
статья, добавлен 25.11.2020Development of a therapeutic and diagnostic algorithm for the blockade of natural fistulas of acute rhinosinocytes. Early diagnosis, study of the etiopathogenetic influence on the main factors in the occurrence and development of these complications.
статья, добавлен 17.02.2023Assessment of the risk of perinatal morbidity in pregnant women with high blood pressure, depending on the severity of preeclampsia, age of pregnant, the level of homocysteine in blood, number of premature births, the degree of delayed fetal development.
статья, добавлен 08.10.2018