Synthesis and antiviral activity of [(9-R1-10-R2-3-R-2-OXO-2H-[1,2,4]-triazino[2,3-c]quinazolin-6-YL)thio] acetamides derivatives with the fragments of carcass amines
Alkylation of potassium 9-R1-10-R2-3-R-2-oxo-2Н-[1,2,4]triazino[2,3-с]quinazolin-6-thiolates by N-cycloalkyl-(cycloalkylaryl-)-2-chloracetamides. Analizes of indicators of the antiviral activity of compounds 3.2 and 3.14 against influenza type A H3N2.
Подобные документы
Study the interaction of an order of amino-anthraquinones with benzoylisothiocyanate. The process of obtaining the formation of new N-benzoyl-N '- (9,10-dioxo-9,10-dihydroanthacen-1- yl) -thioureas. Quantumchemical analysis of the passing reaction.
статья, добавлен 23.02.2016Models of 5,10-methylenetetrahydrofolate in organic synthesis and their reactions. Syntheses using mononucleophiles and binucleophiles. Molecular mechanism of carbon transfer reactions. Designs of models of coenzyme 5,10-methylenetetrahydrofolate.
статья, добавлен 05.03.2013Investigation of the reaction of e-caprolactone with methacrylic acid. Synthesis of the compound chloride with polyethylene glycol ether. Peculiarities of surface active methacrylate monomer. Surface tension in aqueous solution in contact with air.
статья, добавлен 23.02.2016Treating the properties of oxidized activated carbon KAU by different temperatures in inert atmosphere were studied by means of DTA, Boehm titration, XPS and AFM methods and their catalytic activity in hydrogen sulphide oxidation was established.
статья, добавлен 04.04.2014Obtain a carbamazepine nanoemulsion for intravenous administration. The nanoemulsions were evaluated concerning droplet size, zeta potential and drug content. Preliminary studies of anticonvulsant activity for resulting formulation were carried out.
статья, добавлен 30.07.2016Features silver nanoparticles were produced using tannic acid solution as reducing and capping agent. Results of UV-Vis and XRD ensured the existence of silver nanoparticles in the final samples. Nanoparticles with different morphologies were detected.
статья, добавлен 30.07.2016Effect of polymerization copolymers on selenophenes and thiophenes. Analysis of electrosynthesis of selenofen-thiophene copolymers at a constant electrode potential. Stability of oxidation-reduction activity in electrolyte solution based on acetonitrile.
статья, добавлен 30.08.2016Hydrogenation of these oxygen-stabilized n-phases with Ti2Ni-type structure proceeds through expansion of their unit cells by 15.5 and 17.3%, respectively, without change of the type of metal matrix. Insertion of deuterium atoms into the metal matrix.
статья, добавлен 23.02.2017Reactivity and Annulation of Another Ring to an Isoxazole Ring. Reactivity at the Ring Atoms. Reactivity of the Substituents. Syntheses of Condensed Heterocyclic Systems from Aminoisoxazoles. Ring Openings and Rearrangements. Synthesis of Aminoisoxazoles.
статья, добавлен 05.03.2013The study of the processes of reparative activity diacamph part of the medications suppositories for the treatment of degenerative and inflammatory diseases of the rectum, determination of their crystallographic and thermogravimetric characteristics.
статья, добавлен 29.10.2016To study the activity of functional groups of polyurethanes, the characteristics of the stabilization process, the formation of silver nanoparticles. The use of antimicrobial polymeric materials. The interaction of hydrogen bonds between groups of biuret.
статья, добавлен 30.07.2016A chemical compound Triamelon (lodide tris (2,2-trimethylammoniummethylphosphate)) showing before high growth regulatory activity on melons cultures can used as an effective inductor of organogenesis in plant tissue culture of Solanaceae family in vitro.
статья, добавлен 11.02.2014The crystal structure of racemate R,S-7-bromo-3-ethoxy-5-phenyl-3H-1,4-benzodiazepine- has been compared to the structure of R-enantiomer. It has been determined that crystals of R-enantiomer and R,S-racemate are formed by the similar H-bonded chains.
статья, добавлен 01.03.2014Analysis dependence of decomposition rate of adsorbed aluminium choride from rate feed of water steam. The results of the regeneration of solid sorbents used for the purification of alkylates, obtained by alkylation of benzene with higher olefins.
статья, добавлен 20.09.2018Study of the process of intramolecular cyclization products of epichlorohydrin aminolysis of secondary amines. Analysis of the energy characteristics obtained in vacuum and in acetonitrile solution with water as an "active" solvation partner of reaction.
статья, добавлен 30.10.2016Chemical derivatives of 1,2,4-thiazole as biologically active chemicals intended for the protection of plants for agricultural purposes, such as biocides and fungicides when preserving books. Impact of chemicals on humans, animals and the environment.
статья, добавлен 21.07.2018In this study, the electroplating method used silver on copper ores, which is a coating method by forming a coating on a surface using silver salts as a source of silver and potassium nitrate as a catalyst source. Formation of a complex with a silver ion.
статья, добавлен 16.01.2021Study of kinetics of alkaline hydrolysis reaction of methyl esters of substituted 4,5-dimethoxy-N-phenyl-Anthranilic acids in binary solvent dioxane – water, analysis of the dependence lgkT from the nature and position of substituents in pantranco.
статья, добавлен 29.01.2016The objects of the cultural heritage discovered by archaeologists on the area of ancient Kyiv. The topographical examination the fragments of gold tissues (XI–XVI ad.). Content two kinds of materials: golden spiral threads and light colour flakes.
статья, добавлен 01.04.2014A new universal method of estimating the chemical shifts values of the methylene groups. Change the values of 1H and 13C each methylene group in the result of the conversion by replacing the long fragments –(CH2)K– and –(CH2)I– of the Vice alculated.
статья, добавлен 23.02.2016Physical and chemical properties of the drugs. Reactions to chloride ions Cl- in a solution of AgNO3 in HNO3. Photocolorimetry with painted ferum hydroxamate. Reaction on heterocyclic atom of nitrogen. Using of methods of quantitative determination.
презентация, добавлен 24.11.2016Study of adsorption of cadmium (II) cations on the surface of macroporous amorphous silica with chemically modified b-cyclodextrin, its functional derivatives. The analysis of kinetic curves of sorption within the Lagergren model reaction pseudo order.
статья, добавлен 02.04.2014Plastic additives as a wide range of chemicals used by resin manufacturers, compounds and manufacturers to improve the properties, processing and characteristics of polymers. Features of their chemical composition and conditions of effective use.
статья, добавлен 10.03.2019Tetrahydroxycalix[4]arene, tetraalkoxycalix[4]arenes and tetraalkylcalix[4]resorcinarenes are capable to reversible adsorption on the surface of the hydrophobic support lichrosorb RP 18. Conditions reversed high-performance liquid chromatography.
статья, добавлен 28.08.2016Chemical properties of sodium. Sodium compounds are important to the chemical, glass, metal, paper, petroleum, soap, and textile industries. History of appearance of sodium. The serum sodium and urine sodium.
реферат, добавлен 09.03.2010