Prediction of adverse drug reactions based on chemical properties of drugs using machine learning models
Overview of the chemical property calculation and feature engineering process. Discussion of the model performance on the training set and any validation techniques used. Discussion of the most important features for predicting adverse drug reactions.
Подобные документы
Search of promising plant objects for creating new medicines and their use by the example of herbal collections for dental practice. Analysis of compositions of multicomponent medicines based on the medicinal plant raw material intended for drug therapy.
статья, добавлен 27.08.2016Comparative study of fertility, spermatogenesis and indicators of prenatal development of offspring male rats when co-administered anti-TB drugs. Introduction preparations containing isoniazid, pyrazinamide, rifampicin and ethambutol or streptomycin.
статья, добавлен 20.03.2016Periodization of old age. Pharmacokinetics - fate of the substance in the body. Prescription of drugs in seniors - possible risks. Drug absorption. "Overuse". Inappropriate prescription of medicines. Reduced use of medicines. Safe therapeutic regime.
статья, добавлен 24.05.2021Features of the clinical course of the caries process in children. Eliminating the causes and conditions for the occurrence and development of diseases, increasing the body’s resistance to adverse environmental factors is the main task of prevention.
статья, добавлен 20.03.2024Producing countries classification, providing the population of Ukraine effective, qualitative and safe drugs. General characteristics of the methods of treatment of nicotine addiction. Pharmaceutical companies who supply antinicotine medications.
статья, добавлен 24.02.2016The ability of drugs to epigenetically affect gene expression is considered one of the likely mechanisms of unwanted side reactions. Whole-genome DNA methylation (MspI/HpaII) and its fragmentation in blood lymphocytes of rats against the background.
статья, добавлен 27.12.2023Characteristics and features of caffeine. Lethal acute oral dose of caffeine for humans. Consideration of the drug caffeine as a means of oncological and radiological pharmacology. Protective action against cytogenotoxicity caused by vinblastine.
статья, добавлен 09.05.2022- 33. Biological active substances of natural origin and rheumatoid arthritis, prevention or treatment
Research on non-steroidal anti-inflammatory drugs, which are an option for the symptomatic treatment of rheumatoid arthritis. Disease-modifying antirheumatic drugs. The use of pharmacological treatment schemes in the early stages of the disease.
статья, добавлен 19.03.2024 The rationale for the use of scanning electron microscopy to determine the chemical composition of the tissue. Recognition of different types of paraffin tissue sections and the degree of accumulation of heavy metals by scanning electron microscope.
статья, добавлен 27.06.2016A study of the results of epidemiological surveillance as of October 2012 on the spread of drug-resistant tuberculosis, documented in the countries of Brazil, China, S. India and South Africa. Analysis of the main methods of combating the disease.
статья, добавлен 27.08.2016The program of care for drug-addicted patients, their social and psychological portrait. Elements of medical care. Forms of social rehabilitation and employment assistance. Applying the principles of aftercare in the field of institutional education.
статья, добавлен 04.12.2018Features of pharmaceutical products. Influence of substandard drugs on health and life. Approaches to quality assurance of pharmaceutical products, their analysis and evaluation. The possibility of implementing the proposed approaches quality assurance.
статья, добавлен 16.11.2017Chemotherapy as one of the major tool in the treatment of breast cancer. The main etiology of the development of drug resistance of cancer cells to chemotherapeutic agents. Analysis of the effect of anticancer drugs on the cells of breast carcinoma.
статья, добавлен 27.03.2016Ophthalmic drugs on the pharmaceutical market. Excipients that, to one degree or another, affect the quality indicators of medicines and their shelf life and do not reduce the pharmacological effect. Study of excipients in ophthalmic dosage forms.
статья, добавлен 20.03.2024Natural products can be used as novel therapeutic interventions with improved pharmacological properties targeting tumor cells. Consideration of phytomedicines for adjuvant therapy, ability to diminish adverse effects of chemotherapy in cancer patients.
статья, добавлен 03.09.2024Characterization of determination of the main trends in sales of prescription and non-prescription medicines from domestic pharmacies is one of today’s topical areas of medicine and pharmacy. Prognostication and analysis of indexes of drug sales.
статья, добавлен 26.07.2016The preparation, packaging, storage and use of medicines. The efficacy of the preservative. Drugs with antiviral, anti-inflammatory and antibacterial effect for correction of immunity parameters. Intravenous, oral, external (ointments, suppositories).
статья, добавлен 29.01.2016Treatment of peptic ulcer, anticholinergic drugs that inhibit the action of the vagus nerve on acid-secreting cells, contraindications to use. Recommendations of helicobacter pylori eradication. Prevention , symptoms and treatment of chronic pancreatitis.
презентация, добавлен 08.02.2015Non-cavitated caries pathology and clinical implications. Caries and the amelo-dentinal junction. Dentin exposed caries pathology. Closed and open cariogenic ecosystems. Dentin and pulp reactions. The immune response. Tertiary dentinogenesis and caries.
статья, добавлен 10.12.2013Definition of mood disorders, impact on a global scale and unmet needs. Causes and associations in mood disorders: genetics and pharmacogenetics. Clinical diagnosis and assessment of schizophrenia. Antipsychotic drugs and atypical antipsychotics.
учебное пособие, добавлен 21.03.2014Modeling of disseminated intravascular coagulation syndrome with the drug "Efa-2", made on the basis of the poison of the multi-scaled snake Efa. Creating a new experimental model of DIC syndrome, which would characterize the subacute form of the latter.
статья, добавлен 05.09.2024Determine the effect of diacamph hydrochloride, an antihyperglycemic drug, on the cortisol content in the blood of animals with a combined model of diabetes mellitus and chronic stress. Analysis stress-protective properties of diacamph hydrochloride.
статья, добавлен 27.08.2016Optimizing lipid-lowering therapy and achieving it in three ways: increasing the dosage of statins. The pathogenesis of immune inflammatory reactions and endothelial dysfunction ischemic heart disease in combination with systemic inflammatory diseases.
статья, добавлен 14.07.2016Quality assurance as the combination of organizational arrangements taken to ensure qualitative conformance of drugs with their purpose. Characteristics of the basic medical industries in which worldwide compounding preparations are widely applies.
статья, добавлен 29.10.2016Communication between nurse and patient is an important part of the therapy process. Identifying the skills that health care providers need to acquire during vocational training. Performing the main interventions identified in the nursing process.
статья, добавлен 24.05.2021