Prediction of adverse drug reactions based on chemical properties of drugs using machine learning models
Overview of the chemical property calculation and feature engineering process. Discussion of the model performance on the training set and any validation techniques used. Discussion of the most important features for predicting adverse drug reactions.
Подобные документы
The consequences of the use of psychoactive substances - diseases that lead to mental, somatic and social decompensation. Diagnostics, treatment and rehabilitation of surfactant users. Fundamentals of drug addiction and psychotherapeutic assistance.
??????, добавлен 17.11.2020Causes of maternal mortality associated with hypertensive disorders during pregnancy. Effective medical care for women suffering from complications of preeclampsia. Methods of predicting pathology in pregnant women as a priority task of obstetrics.
??????, добавлен 16.06.2024The study of the antimicrobial properties of tincture sophora japonica and chlorhexidine bigluconate. Methods of treatment of periodontitis, gingivitis and stomatitis. Comparative evaluation of the cost of the use of drugs "Hexoral" and "Fitodent".
??????, добавлен 29.01.2016Effects of cognitive state on eye movements. Facilitation of return, Inhibition of return and Saccadic momentum. Vision, perception, eye movements are limited in their capacity to process sensory information. Neural circuits that underlie eye movements.
????????? ??????, добавлен 18.07.2020Analysis of effectiveness of fixed, free and not traditional combinations of antihypertensive medications in the treatment of patients with arterial hypertension. Use of extended-release form of metoprolol in patients with mild and moderate hypertension.
??????, добавлен 02.10.2024To study features of the course and clinical manifestations of osteoarthrosis of the knee joints and the effect ofsymptomatic slow-acting anti-inflammatory drugs on its course in patients with reduced bone mineral density. Analysis radiological changes.
??????, добавлен 27.02.2021Peculiarities of disorders of psychomotor function and psychoemotional state of ischemic stroke patients according to primary examination data; development of the methodology of physical rehabilitation of ischemic stroke patients at the inpatient stage.
??????, добавлен 27.02.2023Vortioxetine is an antidepressant approved by the FDA for the treatment of major depressive disorder. Objective: To evaluate the efficacy and safety of vortioxetine in patients with depression. Side effects of the drug include nausea and vomiting.
??????, добавлен 03.09.2024Combination of general anesthesia with drug hypotension as a factor in the development of postoperative cognitive dysfunction, decreased concentration and productivity of attention and memory. Advantages of using the neuroprotector choline alfoscerate.
??????, добавлен 26.01.2021Device for the experimental study of the interaction of polarized light with samples of tissues. Discussion of practical reasons for making the system suitable for use in the dermatology clinic. Selecting the wavelength for different light sources.
??????, добавлен 28.09.2016General characteristics of the root anatomy. Familiarity with the features of the instrument, using a dental surgery. Analysis of features of the use of dentin-bonding techniques. Compomers role in surgical dentistry. Preliminary stages of restoration.
?????, добавлен 10.12.2013Clinical importance of QT interval duration in patients with permanent pacemakers. Physiological interpretation, methods of heart rate frequency normalization, changes under PM, reactions on medications in patients with spontaneous and stimulated rhythm.
??????, добавлен 29.09.2016The development of the comparison algorithm of differential diagnostics of schizophrenia and acute reactions to stress in patients who attempted suicide. Analysis of anamnestic data and characteristics of the actual status of this category of patients.
??????, добавлен 22.01.2017Colorectal cancer is one of the most common oncological diseases. This problem becomes especially urgent in the case of the formation of an anemic syndrome in patients, which causes the emergence of a mutual burden syndrome and increases the risks.
??????, добавлен 18.12.2023Pseudophakic cystic macular edema as one of the serious complications encountered after cataract surgery. Evaluation of the effectiveness of treatment of visual impairment. Drug therapy for increasing the central macular thickness of the cornea.
??????, добавлен 20.04.2021The studying of providers in the management of human immunodeficiency virus (HIV). Preferred different treatment regimens. Antiretroviral therapy and multidrug combinations for medication of opportunistic infections. The regimens or new diagnostic tools.
??????, добавлен 11.03.2014?nalysis of Doppler echocardiographic indexes in patients (with syndrome and without UCTD) with first diagnosed Q-myocardial. The features of intracardial hemodynamic disorders in patients with Q-MI. based on undifferentiated connective tissue dysplasia.
??????, добавлен 26.08.2016Analysis of the same histological preparations of lung tissue in 73 patients with different forms of idiopathic interstitial pneumonia. Pathological changes in the lungs. Elimination of alternative diseases through a multidisciplinary discussion.
??????, добавлен 28.11.2016Optimization of diagnosis, prognosis and prevention of neuropsychological disorders in organic diseases of the nervous system. Describing of the clinical case of Vestibular paroxysmia and demonstration of the importance of knowing diagnostic criteria.
??????, добавлен 29.12.2023Pneumothorax is a pathological condition characterized by the accumulation of air in the pleural cavity, which leads to loss of negative pressure and collapse of the lung. Traditionally, pneumothorax is divided into traumatic and spontaneous.
??????, добавлен 11.12.2024Study of the possibility of application in the complex of treatment measures of the drug Zincit in order to increase the effectiveness of treatment of patients with diabetes mellitus. Results of complex evaluation of glycemic control in patients.
??????, добавлен 01.12.2017Characteristics of rheumatoid arthritis as one of the risk factors for adverse cardiovascular events. Evaluation cardiovascular risk in patients with rheumatoid arthritis. Analysis of additional factors of cardiovascular risk in patients with arthritis.
??????, добавлен 14.07.2016The chemical composition standardization parameters for the bay laurel plant raw material have been determined on the basis of the research conducted. The results obtained are necessary for developing the project of quality control methods "Lauri Cormus".
??????, добавлен 29.10.2016Regular exercise - a component of improving the health of people with metabolic diseases. Nutrition and eating habits. Recommendations for physical training for the prevention and control of non-communicable diseases and features of their implementation.
??????, добавлен 26.10.2020- 125. Transoral incisionless fundoplication for gastro-esophageal reflux disease: Techniques and outcomes
Transoral fundoplication with the EsophyX device. Antiemetic prophylaxis with at least two drugs and full muscle relaxation throughout the procedure. Symptomatic responses after transoral incisionless fundoplica. Factors affecting TIF outcomes.
??????, добавлен 03.03.2020